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- new triazole derivative 新型三唑衍生物
- A new process for preparing the new fungicide-silicon-containing triazole derivative is described. 摘要对一种新型的杀菌剂-含硅的三氮唑衍生物的合成进行了改进,并给出了一条新的合成路线。
- Objective: To study the antifungal activity of the new triazole compounds against candida species . 目的:研究一类新型的三氮唑化合物对念珠菌属真菌的抗真菌活性。
- Posaconazale is a new triazole drug for the treatment and prevention of invasive fungal infections. 泊沙康唑为一新型三唑类抗真菌药,用于治疗和预防侵袭性真菌感染。
- Ten new derivatives of new triazole compounds which contain the ring of 2H-pyrazole were designed and synthesized. 设计并合成了10种含有二氢吡唑环的新三唑类化合物。
- Objective: To study the antifungal activity of the new triazole compounds against candida species. 目的:研究一类新型的三氮唑化合物对念珠菌属真菌的抗真菌活性。
- Methods: The MICs of new triazole compounds were determined in in vitro antifungal tests to evaluate the activities of title compounds. 方法:采用体外抗真菌活性试验,测定化合物的最低抑菌浓度(MIC),从而评价化合物的生物活性作用。
- Four new triazol organic phosphorus compounds with the general formula(I) have been prepared. 合成了四种标题化合物,探讨了其合成方法。
- Results: All new triazole compounds had activity against candida species, especially high activity against candida albicans. 结果:所有24个新的化合物对念珠菌属真菌均有不同的抑制作用,其中对白念珠菌的活性最好。
- The antifungal activity, pharmacokinetics and clinical evaluation of voriconazole,a new triazole antifungal drug with broad antifungal spectrum,are reviewed. 抗生素类,抗真菌;;药代动力学;;循证医学;;三唑类;;微生物敏感性试验;;文献检索课程;;图书馆服务;;信息存储和检索;;药物过敏
- silicon-containing triazole derivative 含硅的三氮唑衍生物
- For clinical reference,the new approaches in pre-clinical and clinical trials of voriconazole,a new triazole antifungal drug,especially results of its pharmacodynamic studies were reviewed. 介绍新一代三唑类抗真菌药活力康唑的临床前和临床研究新进展,尤其是此药的药效学研究结果,为今后临床应用提供参考。
- The studyof triazole derivatives targeted IGPD is mainly reviewed, the enzymology and catalytic mechanism are also describedin this paper. 文中介绍了IGPD的酶学特征与催化机理,并着重概述了以IGPD为靶标的三唑磷酸酯类抑制剂的研究进展。
- Aim To design and synthesis triazole derivatives with the side chain containing 4-substitued-piperazin-1-yl and to investigate their antifungal activities in vitro. 摘要目的设计合成含哌嗪环侧链的三唑醇类化合物并研究其体外抗真菌活性。
- Keywords silicon-containing triazole derivative;fungicide;synthesis; 含硅的三氮唑衍生物;杀菌剂;合成;
- Aim To study the antifungal activities of triazole derivatives bearing tert-butyl group and to compare their antifungal activities with that of the control drugs fluconazole and itraconazole. 摘要目的设计合成含氧取代的叔丁基三唑醇类化合物并研究其体外抗真菌活性。
- Aim To study the antifungal activities of the triazole derivatives with the side chain containing tert-butyl and to compare their antifungal activities with that of fluconazole and itraconazole. 目的设计合成具有叔丁基结构的三唑醇类化合物并研究其体外抗真菌活性。
- I got a new coat in that store last week. 上礼拜我在那家店买了一件新外套。
- The new chairman will shake up the company. 新任董事长将改组这家公司。
- They all cooed over the new baby. 他们对着新生婴儿爱抚地轻声细语。