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- Objective To measure the pharmacokinetic parameter and bioavailability of aciclovir in healthy human body. 目的测定阿昔洛韦片在健康人体内的药代动力学参数及相对生物利用度。
- The pharmacokinetic parameters were calculated and the bioavai-lability and bioequivalence of two formulations were evaluated by DAS program. 用DAS药代动力学程序计算相对生物利用度并评价生物等效性。
- Conclusion The pharmacokinetic parameters of roxithromycin enterosoluble capsules revealed the character of the dosage form. 结论罗红霉素系肠溶胶囊药代动力学参数符合该剂型的特征。
- And to investigate and compare with the pharmacokinetic parameters of t-Res and t-PD in rats. 目的:建立大鼠血浆中t-Res及t-PD浓度的HPLC测定方法,研究比较t-Res及t-PD在大鼠体内的药代动力学行为。
- The pharmacokinetic parameters were calculated by DAS(ver1.0) program and compared by statistic analysis. 用DAS新药开发权威统计软件(Ver1.;0)计算药代动力学参数;并进行统计学分析。
- There is good linear relationship between pharmacokinetic parameters and doses about CAV and AMX. 克拉维酸钾 阿莫西林两组份在体内的主要药动学参数均与其服药剂量呈良好的线性关系
- TLC scanning method for determination of baicalin in rabbits serum and its pharmacokinetic parameters was established. 采用薄层扫描法测定家兔血清中的黄芩甙及在兔体内的药物动力学参数。
- Drug protein binding changes involved in numerous factors in vivo may cause changes of pharmacokinetic parameters. 体内各种因素引起的药物与血浆蛋白结合的改变,可能导致相应的药代动力学参数变化。
- The results showed that the oral pharmacokinetic parameters of both medicines was an open one chamber model. 方法:对家兔做毒性实验和药物动力学研究。
- The pharmacokinetic parameters were calculated by software 3P87 and statistical analysis was performed by software Microsoft Excel. 使用3P87软件拟合药动学参数,Microsoft Excel软件进行数据统计分析。
- AIM: To study the linear relationship between pharmacokinetic parameters and doses about potassium clavulanic acid (CAV) and amoxicillin (AMX). 目的 :研究体内克拉维酸钾 -阿莫西林两组份的主要药动学参数与服药剂量间的线性关系。
- The main pharmacokinetic parameters of 8 Cl Ad in dogs were obtained after single dose and multiple dose iv infusion of 8 Cl A in dogs. 犬单剂量和多剂量静脉点滴8-Cl-A后,计算得到8-Cl-A的代谢物8-Cl-Ad的药动学参数。
- The results showed there were significant differences in pharmacokinetic parameters of difloxacin in pigs between two dosage forms. 肌注给药吸收完全;
- Pharmacokinetic parameters of the combination are not statistically different from those of cefotaxime or sulbactam alone in volunteers. 药动学研究显示头孢噻肟钠和舒巴坦钠分别单独给药与联合给药的药动学参数均无明显变化。
- A TLC scanning method for determination of baicalin in rabbits serum and its pharmacokinetic parameters was established. 采用薄层扫描法测定家兔血清中的黄芩甙及在兔体内的药物动力学参数。
- OBJECTIVE To compare the pharmacokinetic parameters of chlorogenic acid and baicalin in Yinhuang injection and Yinhuang oral solution in rats. 目的比较银黄注射液和银黄口服液中绿原酸和黄芩苷在大鼠体内的的药物动力学特征。
- OBJECTIVE:To measure the concentrations of levofloxacin in aqueous humor after a single eye dripping of drug and calculate the pharmacokinetic parameters. 目的 :测定乳酸左氧氟沙星 (LVFX)滴眼液单次滴眼后不同时间兔眼房水的药物浓度 ,计算其药动学参数。
- Objective To estimate the pharmacokinetic parameters of drug obeying parallel one order and Michaelis-Menten elimination with bolus intravenous administration. 目的估算一级并行米氏消除药物静脉注射给药的药动学参数。
- Administration with food compared to administration in the fasting state results in clinically-significant differences in absorption and other pharmacokinetic parameters. 进食下服药与禁食下服药相比,在吸收和其他药动学参数上会有临床显著性差异。
- The anti-myocardial ischemia effects and the mechanisms of Guanxin Suhe Delayed-Release Capsule(DRC) were preliminarily studied. Toxicity and the main pharmacokinetic parameters of DRC were also studied in this paper. 本文主要对冠心苏合缓释胶囊(DRC)的抗心肌缺血作用及作用机制进行了初步探讨,同时对该药的急性毒性、长期毒性及其药物动力学特性进行了研究。