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- pluronic poloxamer 普流罗尼
- Poloxamer 188 can also inhibit inflammation and resist thrombus. 泊洛沙姆188具有抑制炎症和抗血栓形成作用,注射使用具有一定的安全性;
- When add SLS、poloxamer or sodium deoxycholate , the solubility were decreased. 加入SLS、泊洛沙姆、脱氧胆酸钠后，溶解度较二元体系下降。
- The ear pills were prepared with poloxamer and PEG as basesrespectively. 采用水溶性非离子型表面活性剂聚醚作基质制备吡哌酸耳用滴丸。
- For brain glioma therapy, BCNU-loaded nanoparticles were prepared using Pluronic F68 as surfactant. 以Pluronic F68作表面活性剂,制备了包载卡氮芥(BCNU)的聚乳酸纳米微粒,用于脑神经胶质瘤的治疗。
- The FasL+ chondrocytes mixed with Pluronic F127 were injected subcutaneously into abdomen wall in allogenic porcine. 取FasL+的软骨细胞与可注射性生物材料PluronicF127混合,注射于同种异体猪的腹壁皮下。
- Pluronic F 127 can be used for a carrier for bioactive factors to modify bio derived material. 生物衍生骨经 Pluronic F- 12 7表面修饰后具有良好的细胞相容性 ,可作为负载生物活性分子的载体修饰生物衍生骨。
- Pluronic F-127 can be a safe and effective vehicle of chondrocytes implantation. Pluronic F-127可作为工程化软骨细胞安全有效的载体。
- Pluronic group: 25% Pluronic F-127 was poured into the articular cartilage defects. 单纯支架组只将25%25Pluronic F-127注入股骨内髁软骨缺损区。
- Objective To synthesize copolymers composed of polyacrylic acid and poloxamer 407,and investigate its thermo-sensitive gelling properties in situ. 目的制备丙烯酸和泊洛沙姆407构成的共聚物,研究其温度敏感的原位胶凝性质。
- Objective：To determine the therapeutic effects of Norcantharidin Poloxamer 407 in intratumoral administration to primary liver cancer. 目的：探讨去甲斑蝥素-泊洛沙姆407缓释制剂局部注射治疗肝癌的疗效。
- Forthly,we seleced the optical concentration of non-inonic sufactant poloxamer 188,which could perfectly prevent protein aggregation at 1.0mg/ml. 第四，我们挑选出了非离子表面活性剂泊洛沙姆188的最佳浓度。当其浓度为1.;0mg/ml时能够很好地抑制蛋白质的聚合。
- Conclusion Dissolution in vitro of curcumin can been increased significantly by solid dispersions prepared with poloxamer 188 as carriers. 结论采用泊洛沙姆188制备的固体分散体能显著提高姜黄素的体外溶出度。
- In 1. 5 L Celligen bioreactor, when pluronic F-68 concentration is 0. 10%(W/V) in medium and agation speed is 70r/min the hybridoma cell can grow normally. 在1.;5升GelliGen生物反应器中;培养基添加0
- The dissolution rates in vitro of ursolic acid solid dispersion were obviously raised, and PVP-k30 was a better carrier in increasing the dissolution rate than Poloxamer 188. 以聚乙烯吡咯烷酮为载体制备的固体分散体溶出速度快于泊洛沙姆。
- At last,we develope a stable aqueous rhGH formulation comprising 5mM histidine,1.0mg/ml poloxamer 188,2.5mg/ml phenol,1.5%(v/v) glycerin and 4.0mg/ml NaCl at pH5.6. 基于以上研究我们研究开发出了一种稳定的重组人生长激素液体制剂，含有5mM组氨酸、1.;0mg/mlpoloxamer188、2
- Desai SD,Blanchard J.Evaluation of Pluronic F127 sustained-release ocular delivery systems for pilocarpine using the albino rabbit eye model[J].J Pharm Sci,1998,87(10):1190. 魏刚;徐晖;郑俊民.;原为凝胶的形成机制及在药物控制释放领域的应用[J]
- Method: Solid dispersion systems of ursolic acid in PVP-K30 or Poloxamer 188 were prepared by co-evaporation of the drug and PVP-K30 or Poloxamer 188 ethanol solution. 方法：选择聚乙烯吡咯烷酮K30、泊洛沙姆188两种载体，用溶剂法制备乌索酸固体分散体；
- CLSM system can accurately reflect cytosolic concentration of free Ca 2+ labeled by Fluo-3/AM and Pluronic F-127. TCDD may increase [Ca 2+]_ i, then make some impairment to the heart function of the neonate rats. 应用Fluo3/AM和PluronicF127结合CLSM技术可以精确的反映细胞内游离钙离子浓度,TCDD可能通过某种机制增加心肌细胞[Ca2+]i,从而对乳鼠心脏功能产生一定损伤。
- Using PTX-resistant SKOV-3 tumor cells as an in vitro model of MDR tumor cells, we demonstrated that Pluronic micellar PTX (i.e. P105/PTX or P105L101/PTX) were able to reverse PTX-resistant SKOV-3 tumor cells compared with free PTX solution. 并采用人卵巢癌多药耐药细胞SKOV-3/PTX作为体外多药耐药的肿瘤细胞模型,评价紫杉醇Pluronic胶束逆转肿瘤多药耐药性的作用。
