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- OBJECTIVE:To discuss the progress and the clinical application evaluation of protein tyrosine kinase(PTK) inhibitors. 目的:探讨酪氨酸激酶抑制剂的进展与临床应用评价。
- Objective To approach the mechanism of action of anticancer and the investigation progress of protein tyrosine kinase (PTK). 摘要目的探讨蛋白酪氨酸激酶抑制剂抗肿瘤作用机理及其研究进展。
- Objective To approach the mechanism of action of anticancer and the investigation progress of protein tyrosine kinase(PTK). 目的探讨蛋白酪氨酸激酶抑制剂抗肿瘤作用机理及其研究进展。
- Receptor tyrosine kinase (RTK), a membrane receptor superfamily with intrinsic protein tyrosine kinase activity, has many members and complicated signal transduction pathways. 摘要受体酪氨酸激酶是一个具有内在酪氨酸蛋白激酶活性的膜受体超家族,成员众多,信号转导通路复杂多样。
- Abstract: Brain-derived neurotrophic factor (BDNF) can increase the excitability of hippocampus by activating its receptor tyrosine kinase B and then result in temporal epilepsy. 摘要: 脑源性神经营养因子(BDNF)激活其受体酪氨酸受体激酶B,使海马兴奋性增高,从而促使颞叶癫痫产生。
- DDR2 is a newly identified receptor protein tyrosine kinase, which is composed of three parts: DR region on the N terminus, a long justatransmembrane region (JM) between DR region and transmembrane region, and intracellular region in cytoplasma. DDR2是一类新发现的受体型蛋白酪氨酸激酶,其分子结构由三部分组成:一是N端的DR区,二是在DR与跨膜区之间的很长的邻跨膜区(justatransmembrane region,JM),三是在胞浆内的胞内区。
- ABSTRACT STI571 is one of the target drugs to Bcr/Abl oncoprotein.It is a special inhibitor to the activation of protein tyrosine kinase by interrupting phosphorylation of substrate. 摘 要 STI571 是一种针对Bcr/Abl基因表达产物的靶向治疗药物,可以阻止底物的酪氨酸残基磷酸化,发挥特异性酪氨酸蛋白激酶活性抑制作用,临床研究结果证明对慢性粒细胞白血病的疗效显著优于干扰素及其它化疗药物。
- HTS model for protein tyrosine kinase inhibitors 酪氨酸蛋白激酶抑制剂的高通量筛选模型
- Lymphocyte-specific protein tyrosine kinase 淋巴细胞特异性酪氨酸蛋白激酶
- protein tyrosine kinase inhibitor 酪氨酸蛋白激酶抑制剂
- non-receptor protein tyrosine kinase 非受体酪氨酸激酶
- receptor protein tyrosine kinase RPTK
- receptor protein tyrosine kinase(RPTK) 受体蛋白酪氨酸激酶
- Protein tyrosine kinases play an important role in signal transduction pathways in regulating a number of cellular functions. 蛋白质酪氨酸在一系列细胞活动的信号转导途径中起着重要的作用。
- Lymphocyte specific protein tyrosine kinase p56 (Lck) 淋巴细胞特异性蛋白质酪氨酸激酶p56(Lck)
- Keywords Tyrosine kinase B;adenoid cystic carcinoma;neurotropism;immunohistochemistry; 酪氨酸激酶B;腺样囊性癌;嗜神经性;免疫组织化学;
- Keywords Depression;Hippocampus;Brain-derived neurotrophic factor (BDNF);Tyrosine kinase B (TrkB);BAI-SONG tablets; 关键词抑郁症;海马;脑源性神经营养因子;酪氨酸激酶B;白松片;
- Study of Protein Tyrosine Kinase Activties in Human Blood and Myelogenic Cells 人外周血与骨髓细胞蛋白酪氨酸激酶活性研究
- protein tyrosine kinases inhibitor 酪氨酸激酶抑制剂