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- Parkinson s disease(PD),is a progressively neurodegenerative disorder,resulting from the degeneration and loss of dopaminergic neurons in the substantia nigra of midbrain. 帕金森病是一种以中脑黑质多巴胺能神经元变性缺失为主要病理变化的渐进性神经系统退行性疾病。
- substantia nigra of midbrain 中脑黑质
- Method：Model of hemilateral PD rat was established with injection of 6-hydroxydopamine（6-OHDA） into the substantia nigra of right side brain. 方法：采用6-羟基多巴胺（6-OHDA）注射于脑右侧黑质造成偏侧PD模型。
- It is believed to be jump-started by a loss of neurons in a midbrain region called the substantia nigra. 相信这是可以跳开始，由一个亏损的神经元在中脑区称为黑质。
- It is caused by the death of nerve cells in a midbrain area called substantia nigra. 它是由于中脑塞梅林氏神经节中的神经细胞死亡导致的。
- Change of Ipsilateral Substantia Nigra of Following Middle Cerebral Artery Occlusion 大脑中动脉闭塞后同侧黑质变化的研究
- An study on the substantia nigra of embryo transplants into brain of rat model of paralysis agitans 胚胎黑质植入震颤麻痹模型鼠脑内的研究
- Porta Nigra of Trier. Another view. 特里尔的古罗马城门。另一角度。
- Influence of cyclooxygenase-2 expression on cell apoptosis in substantia nigra of the mice with Parkinson disease 环氧合酶2表达对帕金森病模型小鼠黑质细胞凋亡的影响
- Biochemical changes in substantia nigra of patients with Parkinson disease observed by modified proton magnetic resonance spectroscopy 改良质子磁共振波谱技术观察帕金森病患者黑质内神经代谢的改变
- Changes of HMW MAP-2 in globus pallidus and substantia nigra of rats after low frequency of repetitive transcranial magnetic stimulation 经颅重复性低频磁刺激后大鼠苍白球及黑质HMW MAP-2表达的变化
- Preliminary study on the molecular mechanism for MPTP-induced dopaminergic neuronal degeneration in the substantia nigra of C57BL mice 金荣祥!200065上海市,吕立夏,徐磊,李学礼, 甲基-4-苯基-1,2,3,6-四氢吡啶致黑质多巴胺能神经元变性的分子机制的研究
- The disease affects a small area of cells in the middle of the brain called the substantia nigra. 该疾病侵袭大脑中部一小部分被称为黑质的脑细胞。
- Many GABA-like positive fibres were observed at the inferior colliculus level of substantia nigra. 在下丘平面还可见到许多GABA样阳性神经纤维。
- No correlations were found in the volumes of the caudate, putamen, globus pallidus, substantia nigra with H&Y range. 结论：PD病人壳核体积大小与疾病严重程度呈负相关。
- Conclusions Passive smoking can partially protect DA neurons of substantia nigra from the damage of 6-OHDA. 结论被动吸烟可减轻6-OHDA对黑质DA能神经元的损伤。
- Parkinson's disease (PD) is a neurologic disorder characterized by dopaminergic cell death in the substantia nigra. 帕金森氏病（PD）是一种以黑质多巴胺能细胞死亡为特征的神经疾病。
- Conclusion Passive smoking can protect DA neurons of substantia nigra from the damage of 6-OHDA. 结论被动吸烟能减轻黑质纹状体DA能神经元的损伤。
- Initial results in a handful of patients suggested that symptoms had improved, and PET scans indicated some restoration in dopamine uptake in the striatum and substantia nigra. 这一小群患者的初步结果显示症状得到改善，而正子断层扫描则指出，纹状体与黑质多巴胺的吸收也有些进步。
- A marked antiepileptic effect was observed during stimulation of periaqueductal gray of midbrain and N. accumbens. 电刺激中脑导水管周围灰质及伏隔核有显著制痫作用。
