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- Keywords chemical synthesis;sunitinib malate;antitumor agent;tert-butyl acetoacetate; 化学合成;苹果酸舒尼替尼;抗肿瘤药物;乙酰乙酸叔丁酯;
- sunitinib malate 苹果酸舒尼替尼
- Calcium citrate malate is more suitable for achlorhydria. 果酸钙更适合于胃酸缺乏的人群补钙。
- Why did the addition of oxaloacetate or malate stimulate oxygen consumption? 为什么草酰乙酸或苹果酸的加入促进了氧的消耗?
- Conclusion:Calcium citrate malate is more suitable for achlorhydria. 结论:果酸钙更适合于胃酸缺乏的人群补钙。
- Objective:To investigate the dissolution of calcium citrate malate tablet. 目的:研究果酸钙片的溶出度。
- Sunitinib probably has a higher potency in terms of anti-angiogenesis but in some cases this may have a deleterious effect. 舒尼替尼可能有较强的抗血管生成能力，但在某些情况下，这可能有有害的影响。
- This leaves the mitochondrion and is converted back to oxaloacetate in the cytosol by cytoplasmic malate dehydrogenase. 苹果酸离开线粒体 , 在胞质溶胶中被苹果酸脱氢酶又转变回到草酰乙酸。
- Why was the amount of oxygen consumed so much greater than the amount necessary to completely oxidize the added oxaloacetate or malate? 为什么加入草酰乙酸或苹果酸后耗氧量比完全氧化所需的多出如此之多?
- The activity of sorghum leaf NADP-malic enzyme appeared to be modulated by pH, malate, Mg~(++) and Mn~(++). pH、Mg~(++)、Mn~(++)和苹果酸对高粱叶片NADP-苹果酸酶活力具有不同程度的调节作用;
- The malate permease, encoded by mleP gene, is important for assisting malolactic fermentation (MLF). 苹果酸通透酶具有协助苹果酸乳酸发酵(MLF)的重要功能。
- Malate dehydrogenase (MDH) is an essential metabolic enzyme, which has high economic value in protein research. 苹果酸脱氢酶不仅是一种重要的糖代谢酶，而且具有较高的经济价值和理论研究价值。
- No difference in malate dehydrogenase(MDH) and esterase isozyme patterns were detected among the strains. 结果表明,24株大丽轮枝菌苹果酸脱氢酶酶谱具有种的特异性,酯酶酶谱具有属的特异性。
- Sucrose accounted for about 65% of the total sugar, and malate for about 50% of total acid contents i n fruits. 结果表明,桃果实中的可溶性糖和酸主要是蔗糖和苹果酸,分别占总可溶性糖的65%25左右和总酸含量的50%25。
- Objective To obtain a new-type calcium nutrient supplement of calcium citrate malate compound salt(CCM). 目的研制柠檬酸-苹果酸复合钙盐新型钙营养强化剂。
- Mg increased the secretion of citrate and malate by 13.1% and 22.1% while Zn increased the malate exadation by 22.1%. Mg2+使铝诱导的柠檬酸分泌量增加13.;2%25，苹果酸增加22
- Conclusion: Sunitinib has antitumor activity in pancreatic neuroendocrine tumors;its activity against carcinoid tumors could not be definitively determined in this nonrandomized study. 结论：舒尼替尼对胰腺神经内分泌肿瘤患者有抗肿瘤作用，在本次非随机试验中对类癌的作用尚不确定。
- Conclusion: Sunitinib has promising single-agent activity in patients with recurrent NSCLC, with an ORR similar to that of currently approved agents and an acceptable safety profile. 结论：舒尼替尼对于复发性非小细胞肺癌病人，是一种有希望的单药治疗方案，其总有效率与当前已经证实有效的药物获得的效果相似，并且副反应是安全的和可接受的。
- It recently studied the herb Rhodiola rosea, also known as roseroot, and is due to evaluate the supplement citrulline malate. 为了评估补充物的瓜氨酸苹果酸，空军最近研究了中药红景天,亦称蔷薇根景天。
- They are ICL( isocitrate lyase), CS(citrate synthase),MDH(malate dehydrogenase), MS(malate synthase) genes and they are named as OsICL,. 此外,克隆四个水稻乙醛酸循环酶基因:OsICL(异柠檬酸裂解酶)、OsCS(柠檬酸合成酶)、OsMS(苹果酸合成酶)和OsMDH(苹果酸脱氢酶)。
