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- Sulfadiazine-polylactide,a tumor targeting drug carrier,was successfully synthesized by the phase transfer catalysis(PTC)with tetrabutyl ammonium chloride hydroxide as catalyst. 采用相转移催化法以四丁基氯化铵为催化剂合成了端基含磺胺嘧啶的聚乳酸,将肿瘤导向基团引入了可生物降解药物载体。
- Keywords attapulgite;magnetic particle;targeting drug carrier;simulate gastric juice;simulate intestines liquid; 关键词凹凸棒石;磁性粒子;靶向药物载体;模拟胃液;模拟肠液;
- Keywords randomly 50% N-acetylated low molecular weight chitosan (LMWC);renal targeting drugs;drug delivery;prednisolone conjugates;drug carriers; 乙酰度的低分子量壳聚糖;肾靶向药物;药物传递;泼尼松龙结合物;药物载体;
- targeting drug carrier 靶向药物载体
- Keywords starch microemulsion;microreactor;Starch nanoparticles;starch microgel;targeting drug carrier;adsorptive mechanism;biexponential and biphase kinetics function;controlled release properties; 关键词淀粉微乳;微型反应器;淀粉纳米粒;淀粉微凝胶;靶向药物载体;吸附机理;双指数双相动力学方程;缓释性;
- Polysaccharides, pectin, dextran, guar gum and chitosan have been used or tested for targeted drug delivery in pharmaceutical applications. 多聚糖如海藻酸盐、胶质、右旋糖苷、凝胶已在制药应用中用于或正试验用于药物的靶向传输。
- CONCLUSION:Colloidal drug carriers may affect the targeting of CyA to mononuclear phagocyte system. 结论:将环孢菌素A包埋于胶体亚微闰中可以改变其对巨噬细胞的靶向性。
- Research on colloidal drug carriers is the most active area in nano-technology concerned with pharmic research. 胶体药物载体的纳米技术是在药学研究中最活跃的领域。
- A kind of polymer drug,using 5-flurouril as model drug,lactic acid-phosphate copolymers as polymer drug carriers,was synthesized. 以5-氟尿嘧啶(5-FU)为药物模型,以乳酸-磷酸酯共聚物为高分子药物载体,合成了侧链带药的乳酸-磷酸酯共聚物药物。
- Hyaluronic acid(HA) is a very good drug carrier due to its excellent biocompatibility and biodegradability. 透明质酸(HA)具有良好的生物相容性和生物降解性,是优良的药物载体。
- The main characteristics, types and surface modifications of colloidal drug carriers are reviewed, and several notable problems are pointed out. 综述了其主要特点、类型和表面修饰等问题,并提出了该领域值得注意的若干问题。
- Polymeric micelles self-assemblied by amphiphilic block copolymers in aqueous media are thought to be promising drug carriers with nanometer size. 由两亲性聚合物形成的胶束是一种很有发展前景的纳米级药物载体。
- Biodegradable macromolecule carried controlled drug releasing and biodegradable macromolecule carried targeted drug delivery are the focus of recent investigation in macromolecular medicine. 生物可降解型高分子载体控制释放药物和生物可降解型高分子载体靶向药物是近年来高分子药物研究的重点。
- Hyaluronic acid (HA) is a very good drug carrier due to its excellent biocompatibility and biodegradability. 摘要透明质酸(HA)具有良好的生物相容性和生物降解性,是优良的药物载体。
- This review presents the related factors of the metastsis of lung cancer and the related new targeted drugs. 本文就肺癌转移的各个参与因素以及相关的新靶向药物的临床研究作一综述。
- Using transferrin as a drug carrier can render the absorption of peptide and protein in gastrointestinal tract. 以转铁蛋白作为药物载体,可以使蛋白肽类药物在肠道吸收;
- Targeted drug delivery system (TDDS) is a hot issue in Pharmaceutics After long time pursuing, people become to realize the targeted mechanism, property, biodistribution and pharmacokinetics of TDDS. 卵巢癌是女性常见的肿瘤之一,极大地危害了女性的健康,目前治疗手段不甚理想,因此设计一种能将药物靶向于卵巢癌细胞的给药系统更具有实际意义。
- Dendrimers as drug carriers and their applications to the areas of antiviral, anti-tumor, peptide and saccharide analogues are discussed. 简要综述了树枝状化合物作为药物载体及其在抗病毒、抗肿瘤以及多肽和糖模拟物等领域的研究进展。
- Now that there are several targeted biotech drugs on the market, researchers are starting to test whether two targeted drugs are better than one. 既然市场上有很多靶向生物技术药物,那么研究者正开始试验两个靶向药物是否会比一个更好些。
- Survival of advanced CRCs has achieved more than 24 months with the use of new chemotherapeutic agents, especially when combining with molecular targeted drugs. 与此同时,新的治疗方法和药物也在不断问世,分子靶向药物是发展最快的一个方向,特别是单克隆抗体与传统的化疗药物的联合已经使得晚期大肠癌患者的生存期超过了24个月。