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- OBJECTIVE To improve the synthetic procedure of terazosin hydrochloride. 目的改进盐酸特拉唑嗪的合成工艺。
- METHODS Terazosin hydrochloride was synthesized from anhydro-piperazine via acylation,reduction,amination,salification etc. 方法以无水哌嗪为起始原料,经酰化、还原、胺化、成盐等反应制得盐酸特拉唑嗪。
- Objective To establish a method for determining related substance of terazosin hydrochloride capsules by thin layer chromatography. 目的采用薄层色谱法测定盐酸特拉唑嗪胶囊中有关物质。
- To establish a internal standard HPLC method for the determination of terazosin hydrochloride in terazosin hydrochloride tablets. 建立了盐酸特拉唑嗪片中盐酸特拉唑嗪的含量测定的HPLC内标法。
- Terazosin hydrochloride dihydrate was synthesized from 6,7 dimethoxy 1 H,3H quinazolin 2,4 dione via chlorination, amination, condensation and salt formation in an overall yield of 64.3%. 以 6 ;7-二甲氧基 - 1H;3H-喹唑啉 - 2 ;4-二酮为原料 ;经氯化、氨化、缩合、成盐制得盐酸特拉唑嗪 ;总收率6 4.;3%25。
- Synthesis technology improvement of terazosin hydrochloride 盐酸特拉唑嗪的合成工艺改进
- Application of terazosin hydrochloride in prostate diseases 盐酸特拉唑嗪在前列腺疾病中的应用
- Keywords Terazosin hydrochloride;Treatment;Primary hypertension; 盐酸特拉唑嗪;治疗;原发性高血压;
- Keywords fluorescence spectroscopy;Terazosin hydrochloride;content; 荧光法;盐酸特拉唑嗪;含量;
- Determination of terazosin hydrochloride capsules by fluorescence spectroscopy 荧光法测定盐酸特拉唑嗪胶囊的含量
- Keywords terazosin hydrochloride;ion-selective electrode;gel;determination; 盐酸特拉唑嗪;离子选择性电极;凝胶;测定;
- Keywords Terazosin hydrochloride capsules;stability;contents determining; 盐酸特拉唑嗪;稳定性;含量测定;
- Studies of the stability and determination on the dissolution of terazosin hydrochloride tablets 盐酸特拉唑嗪片的稳定性研究及溶出度测定
- Determination of related substance of terazosin hydrochloride capsules by thin layer chromatography 薄层色谱法测定盐酸特拉唑嗪胶囊中有关物质
- Clinical study on domestic terazosin hydrochloride for treatment of essential hypertension 国产盐酸特拉唑嗪片治疗原发性高血压的临床研究
- Keywords chromatography;thin layer;terazosin hydrochloride capsules;related substance; 色谱法;薄层;盐酸特拉唑嗪胶囊;有关物质;
- Keywords RP-HPLC;Terazosin hydrochloride;Blood concentration of drug;Fluorescence detector; 高效液相色谱法;盐酸特拉唑嗪;血药浓度;荧光检测器;
- Keywords Terazosin hydrochloride;Prazosin hydrochloride;Alfuzosin hydrochloride;Fluorescence quenching;Bovine serium albumin; 盐酸特拉唑嗪;盐酸阿夫唑嗪;盐酸哌唑嗪;荧光猝灭;牛血清白蛋白;
- The comparative clinical study on the efficacy and safety between Naftopidil tablet and Terazosin hydrochloride tablets in the treatment of benign prostatic hyperplasia 萘哌地尔与盐酸特拉唑嗪治疗良性前列腺增生的疗效与安全性评估
- a joint-stock company covering research,manufacturing and trade of terazosin hydrochloride,doxazosin mesylate,prazosin hydrochloride,glimepirde,leflunomide,etc. 生产盐酸特拉唑嗪、甲磺酸多沙唑嗪、盐酸哌唑嗪、盐酸安普乐定、来氟米特、4,4'对二氟苯甲酮、4,4'对二氟苯甲醇、4,4'对二氟苯甲哌嗪等。