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- OBJECTIVE To characterize the theological properties of thermosensitive in situ gel for better understanding the process of thermal gelification in situ. 目的应用动态流变实验测定温度敏感原位凝胶的流变性质,以预测其在体胶凝(相变)行为。
- The development of polymers must play an increasingly important role in the speed evolution of thermosensitive in situ gels. 聚合物的开发应用必将不断地促进温度敏感型原位凝胶的快速发展。
- Keywords thermosensitive in situ gel;poloxamer;diffusion; 温度敏感凝胶;泊洛沙姆;扩散;
- Keywords Dexamethasone Pharmacokinetics Thermosensitive in situ gel Cochlea Intratympanic injection; 地塞米松;药动学;温度敏感原位凝胶;耳蜗;鼓室注射;
- Keywords thermosensitive in situ gel;dexamethasone;sustained-release;poloxamer 407;deafness; 温度敏感原位凝胶;地塞米松;缓释;泊洛沙姆407;耳聋;
- Keywords thermosensitive in situ gel;dexamethasone sodium phosphate;poloxamer 407; 温度敏感原位凝胶;地塞米松磷酸钠;泊洛沙姆407;
- Keywords recombinant human growth hormone;thermosensitive in situ gel;poloxamer; 重组人生长激素;温度敏感型原位凝胶;泊洛沙姆;
- Keywords thermosensitive in situ gel;poloxamer;sol-gel transition temperature;gelation temperature;stable viscosity;elastic modulus; 温度敏感原位凝胶;泊罗沙姆;相转变温度;胶凝温度;稳态黏度;弹性模量;
- thermosensitive in situ gel 温度敏感原位凝胶
- Keywords Thermosensitive in situ gel;Solid lipid nanoparticle;Tympanic drug delivery system;Dexamethasone;Blood-inner ear barrier;Round window;Intratympanic administration;Poloxamer;Compritol 888 ATO; 温度敏感原位凝胶;固体脂质纳米粒;耳腔给药系统;地塞米松;血-内耳屏障;圆窗;鼓室给药;泊洛沙姆;山榆酸甘油酯;
- Abstract: Objective To prepare thermosensitive ocular in situ gel for tiopronin in the purpose of prolong the retention time of drug on cornea. 摘要:目的 筛选硫普罗宁温度敏感型眼用原位凝胶最优处方,提高药物在角膜前的滞留时间。
- Results The intranasal administration of the in situ gel of gastrodin produced... 结论天麻素鼻用原位凝胶具有一定的脑靶向性与缓释作用。
- Conclusion The in situ gel of tiopronin prolonged drug effect, and reached the purpose of delayed release. 结论 硫普罗宁眼用原位凝胶延长了药物在眼部的作用时间,达到了缓释的目的。
- Objective To investigate the biodistribution of gastrodin ion-activated nasal in situ gel in rat blood and brain tissues and to evaluate its brain targeting. 目的研究天麻素离子敏感鼻用原位凝胶在大鼠体内血液与脑组织中的药物分布,并评价其脑靶向性。
- Recently, in tissue engineering injectable, in situ gel forming systems which reduce invasion of implantation to host tissues to the full extent have been reported. 组织工程采用可注射原位形成水凝胶,与预成型支架相比具有特定的优势:能填充任意形状的缺损,并在很大程度上降低植入对机体组织的侵入性,且能与各种治疗药物混合。
- Keywords Penciclovir;Thermosensitive in situ forming gel;Pluronic;Rheology;Drug release;Ocular irritation;Pharmacokinetics; 喷昔洛韦;温度敏感原位凝胶;普朗尼克;流变学;药物释放;眼部刺激;药代动力学;
- Biopolymer can be triggered in situ to form a gel. 对生物矿化作用的进一步研究有助于微生物调剖机理的完善和应用。
- Key around Mobile, the next key stop in situ fixed. 左右键移动,下键停在原地不动。
- Lobular carcinoma in situ is seen here. 图示小叶原位癌。
- Fluorescence in situ hybridization See FISH. 荧光原位杂交:参见FISH.