- advance despite difficulties; go upstream undauntedly; keep advancing in defiance of [in spite of] difficulties; press [go] ahead [forward] in the face of difficulties; press ahead, knowing well there are difficulties; Recognizing the difficulties before him, he went ahead just the same.; take [seize] the bull by the horns; Well aware that there are difficulties ahead, (he) goes on undeterred.:
press forward without giving up halfway
知难而进，绝不半途而废
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