Adjuvant systemic therapy: Patients with LCIS are treated with daily oral tamoxifen. If tamoxifen is unsuitable or refused, bilateral mastectomy may be considered.

• 辅助性全身疗法：LCIS病人每天服用他莫昔芬治疗。如不适合服用节莫昔芬或病人拒绝接受，可考虑双侧乳房切除术。