Aim:To observe change of binding activity of HIF-1 with erythropoietin(EPO) hypoxia response element(HRE) in the hippocampus of mice preconditioned to hypoxia and explore relationship between the changes and the preconditioning.

• 目的:观察低氧预适应对小鼠海马组织HIF-1与EPO的低氧应答元件(HRE)结合活性的变化,探讨这种变化与低氧预适应形成的关系。