Aneurysm and AVM ECs expressed von Willebrand factor, Adrenomedullin, and exhibited a progressive reduction of proliferation and in vitro angiogenic ability after the V passage.

• 来源于动脉瘤和动静脉型血管畸形的内皮细胞培养5代以后表达血管假性血友病因子、肾上腺髓质素，同时在活体外增殖及生成血管的能力方面呈顺行性退化。