As for activities of SDH,which affected by high dose VPA in infants,were significant decreased by 44.8% and 57.9%,respectively,but still in normal range in adult groups.

• 检测肝线粒体呼吸链关键酶琥珀酸脱氢酶(SDH)活性表明；仅有较大剂量VPA/VPA+PB婴儿鼠SDH活性与对照组差异有显著性(P<0.；01)；分别降低44