CPU86017 or zh-001 to zh-004(the 4 stereoisomers of CPU-86017) was administered in gradient dosage to rat aorta in vitro for evaluation the effects on aortic contraction induced by Phe and KCl.

• 通过对大鼠离体主动脉梯度给予CPU-86017或zh-009-zh-012,研究其对去氧肾上腺素(Phe)或KCl引发的血管收缩活性的影响。