Conclusion Both invasion ability and collagenolytic activity of U87MG cells are depended on MMP2, suggesting that MMP-2 plays an important role in glioma invasiveness.

• 结论：U87MG胶质瘤细胞的侵袭能力和胶原降解作用取决于MMP-2，提示MMP-2在胶质瘤侵袭生长中起重要作用。