Expression of eN0S, V1P, SP, NPY was founC1 in HUVECboth in vivo and in vitro, which suggested endothe l ial ce11scou1d regu1ate non--innervated b1ood vessel s v iaautocr ining/paracr ini ng mu1 t ipl e vasoact i ve subs tances.

• 采用兔疫组化、免疫荧光的方法证实在体和离体的脐血管内皮细胞中均表达eNOS、VIP、SP、NPY，提示脐血管内皮细胞能通过巳DRF途径或旁分泌多种VPS途径来调控脐血管的张力。