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- One way they do this is by acetylation of the H3 histone's fourth amino acid, also a lysine.The effect is to open the chromatin at that site, making the DNA accessible. 其作用方式之一是使H3组蛋白的第4个氨基酸(也是赖氨酸)残基乙酰化,使染色质在这一部位展开,而DNA变得易于接近。
- H3 histone H3组蛋白
- Su(ar)3-9 proteins attach methyl groups to the histone labeled H3 at its ninth amino acid residue, which is a lysine. 9蛋白将甲基加在组蛋白H3的第九位氨基酸残基,也就是赖氨酸残基上,从而使H3组蛋白贴上了个标签。
- SET domain proteins of SUV3-9H family specifically methylate the residue lysine 9 of histone H3, resulting in gene silencing. Su(var)3-9家族的SDP专一甲基化组蛋白3第9位赖氨酸(H3K9),从而导致基因沉默(gene silencing)。
- This study was to investigate the effects of curcumin on the acetylation of histone H3 and the expression of p21WAF1/CIP1 gene in human lymphoma cell line Raji. 本研究探讨姜黄素对Raji细胞组蛋白H3的乙酰化作用和细胞周期素依赖性激酶抑制剂p21WAF1/CIP1基因表达的影响。
- Our lab will explore the molecular mechanism and biological functions of histone H2B mono-ubiquitination and its downstream histone H3 methylation events. 本实验室将对H2B单泛素化及其下游H3赖氨酸甲基化的分子机制和生物学意义进行研究。
- "The aurora B protein is responsible for phosphorylating histone H3 - a protein involved in the structure of chromatin (the strands of DNA that make up chromosomes) in cells. 激光蛋白B和参与染色体结构中的组蛋白H3的磷酸化相关。
- The histone code will not be easy to crack. 组织蛋白的密码不是那么容易破解的。
- H4+ cluster ion and its neutral cluster product H3[J]. 引用该论文 杨百方;缪竞威;杨朝文;师勉恭.
- A nucleoprotein whose protein component is a histone. 核组蛋白蛋白成分是组蛋白的核蛋白
- A nucleoprotein whose protein componentis a histone. 核组蛋白蛋白成分是组蛋白的核蛋白。
- In HTML, it is structured by using heading tags such as H1, H2, H3, and H4 . 在HTML中,它的结构是使用标题标签例如H1,H2,H3,和H4。
- A smaller version, the H3, was built by GM at a plant in Shreveport, La. 通用汽车公司则在路易斯安纳州什里夫波特市(Shreveport)自行生产体积稍小的悍马H3民用版本汽车。
- So unsurprisingly the H10's results are more or less identical to the H3' s. 有关的H10使用相同的稳定系统,作为它的前身。
- Study on histone acetylation in myoblast cultures of DMD chicken embryo. 进行性肌营养不良鸡胚成肌细胞组蛋白的乙酰化研究。
- Histone acetylation/deacetylation is closely related to the regulation of gene. 组蛋白乙酰化/去乙酰化与基因调控密切相关。
- Histone lysine methylation plays a key role in epigenetic regulation. 摘要组蛋白赖氨酸的甲基化在表观遗传调控中起着关键作用。
- Histone modifications are implicated in influencing gene expression. 组蛋白修饰与影响基因表达有关。
- Histone deacetylase inhibitors had been used to treat cancer and leukemia. 组蛋白去乙酰化酶抑制剂已经越来越多的被用于治疗肿瘤和白血病。
- P1: Female bisexual; P2: Rare male; H1, H2 and H3: groups of hybird progeny. Dotted lines delimit none interpreted activity zones. 两性卤虫;P2:罕见雄体;H1、2和H3:为杂交后代类型。虚线区表示未做分析的活性区域。