However, thiazolidine-diones can cause weight gain, fluid retention and edema,and bone loss which has been reported in resent years.

• 该类药物除主要用于糖尿病的预防和治疗外,在心血管疾病、炎症、牛皮癣、肿瘤等疾病的预防或治疗方面也显示出良好前景。