Human bladder transitional cell cancer BIU 87 cells and multidrug resistant BIU 87/ADM cells were treated with daunorubicin (DNR) combined with JSB 1 and CsA alone or together and with JSB 1 and verapamil(Ver) alone or together.

• 为了证实抗P?糖蛋白（P?gp）单克隆抗体协同环孢素A（CsA）逆转人膀胱癌耐药细胞亚株的抗药性以及建立能有效地克服MDR的治疗方案，对人膀胱移行细胞癌BIU?87细胞系和BIU?87/ADM耐药细胞亚株经柔红霉素（DNR）与抗P?gp单克隆抗体JSB?1和单独或联合CsA；