If a spot is bigger or smaller in diseased tissue compared with healthy tissue, or if a protein appears or disappears completely, investigations can be focused on the protein in question.

• 如果在有病的组织中的某个点大了或小了(与健康组织比较)，或者一种蛋白质出现或完全消失了，研究工作就可以集中在这个有问题的蛋白质上。