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- Objective: To introduce inhaled iloprost for the treatment of primary pulmonary hypertension. 摘要目的:介绍治疗原发性肺动脉高压的吸入性伊洛前列素。
- In 9 patients on chronic intravenous prostanoids, 8 transitioned from intravenous prostanoids to inhaled iloprost, which continued during follow-up. 9例长期静脉应用类前列腺素的患者中,8例从静脉应用类前列素改为吸入伊洛前列素并且在随访期间一直持续应用。
- Results and Conclusion: Inhaled iloprost can reduce pulmonary vascular resistance and delay the development of primary pulmonary hypertension. 结果和结伦:吸入性伊洛前列素治疗可以降低肺血管阻力和延缓原发性肺动脉高压的进程。
- Background: Inhaled iloprost has been approved for the treatment of adults with PAH, but little is known about the effects in children with PAH. 背景:吸入伊洛前列素被证实可用于治疗成人PAH,但其对儿童PAH的作用尚不清楚。
- Conclusion Inhaling iloprost and pulmonary injection of phentolamine can both effectively differentiate the functional and occlusive PAH in CHD. 酚妥拉明用药前后,肺循环和体循环的压力、阻力和血流量都有明显变化。
- Results and Conclusion:Inhaled iloprost can reduce pulmonary vascular resistance and delay the development of primary pulmonary hypertension. 结果和结论:吸入性伊洛前列素治疗可以降低肺血管阻力和延缓原发性肺动脉高压的进程。
- Conclusions: Inhaled iloprost caused sustained functional improvement in some children with PAH, although inhaled iloprost occasionally induced bronchoconstriction. 结论:吸入伊洛前列素对部分PAH儿童有长期的功能改善,虽然偶尔导致支气管收缩。
- Of those patients, 32 were selected to receive inhaled iloprost (a prostacyclin analog) along with bosentan, while the remainder took a placebo and bosentan. 在这些病人中,32例采用吸入性伊洛前列素(一种前列腺幻素的类似物)和波生坦的联合用药,其余病人采用安慰剂和波生坦治疗。
- Acute iloprost inhalation reduced forced expiratory volume in 1 s and mid-volume forced expiratory flow by 5% and 10%, respectively, consistent with acute bronchoconstriction. 急性伊洛前列素吸入分别降低1秒用力呼气量和呼气中段流速5%25和10%25,与急性支气管收缩一致。
- Sixty-four percent of patients continued receiving long-term iloprost therapy, 36% stopped iloprost, due to lower airway reactivity, clinical deterioration, or death. 64%25患者继续使用长期伊洛前列素吸入、36%25患者因为低气道反应性、临床恶化或死亡而停止使用伊洛前列素。
- Results: Acute administration of inhaled iloprost lowered mean pulmonary artery pressure equivalent to the response to inhaled nitric oxide with oxygen. 结果:吸入伊洛前列素对肺动脉压力的降低与吸入一氧化氮加氧气的作用相等。
- Zangeler E G, Hinsbergh V W. Norepinephrine and iloprost improve barrier function of human endothelial cell monolayers. Role of cAMP\[J\]. Am J Physiol 1994,260(5):c1052-1058. 黄崭;陈凇娟.;卡维地洛治疗高血压的临床疗效及对血脂、糖代谢的影响\\[J\\]
- Cardiac catheterization, standard lung function testing before and after iloprost inhalation, 6-min walk test, World Health Organization functional class, and hemodynamic parameters were monitored. 研究监测了吸入前后的心导管检查、标准肺功能检查,6分钟步行实验、世界卫生组织功能分级和血流动力学指标。
- Keywords iloprost;administration;inhalation;review;hypertension;pulmonary; 伊洛前列素;投药;吸入;综述;高血压;肺性;
- Keywords partial liquid ventilation;perfluorocarbon;acute lung injury;iloprost; 部分液体通气;全氟化碳;急性肺损伤;伊洛前列素;
- Inhaled iloprost in eight heart transplant recipients presenting with post-bypass acute right ventricular dysfunction 对八例行心脏移植术、转流后出现急性右心室功能不全的患者吸入依洛前列素的报道
- Ilomedin 伊落前列素, 伊洛前列[周围血管扩张药]
- Keywords acute lung injury;acute respiratory distress syndrome;perfluorocarbon;partial liquid ventilation;Iloprost;hypoxemia;pulmonary hypertension; 急性肺损伤;急性呼吸窘迫综合征;部分液体通气;油酸;伊洛前列素;低氧血症;氧合指数;肺静态顺应性;
- iloprost 伊洛前列素<前列腺素类药>