In areas with high HBV endemicity, perinatal transmission is the main route of transmission, whereas in areas with low HBV endemicity, sexual contact amongst high-risk adults is the predominant route.

• 在HBV的高毒力区内，围产期是最主要的感染途径，而在低HBV毒力的地区，高危人群之间的性是传染的主要传播途径。