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- Objective To elucidate the multidrug resistance(MDR) in bladdertransitional cell carcinoma. 目的研究膀胱移行细胞癌的多药耐药性。
- However, multidrug resistance (MDR) presents an important obstacle for the success of the treatment. 对瘤组织而言,多药耐药是化疗失败的主要原因。
- However,the multidrug resistance (MDR) of nasopharyngeal carcinoma is the key role in the failure of the treatment. 而多药耐药(MDR)机制是导致其化疗等综合治疗失败的主要原因。
- Conclusions The multidrug resistance (MDR) in endometrial carcinoma may be related with the expression of MDR1 gene. 结论子宫内膜癌对化疗的耐药可能是一种固有性MDR,这可能与MDR1基因的表达有关。
- Objective To study the relationship between p16,bcl 2 expression and multidrug resistance (MDR) in adenocarcinoma of colon. 目的 研究大肠腺癌p16、bcl-2 表达与多药耐药性的关系。
- Objective To study the reversal effects of droloxifene (DRO) on multidrug resistance (MDR) in MCF7/ADR and its mechanism. 目的:研究屈洛昔芬(DRO)对乳腺癌耐药细胞株(MCF7/ADR)多药耐药性(MDR)的影响。
- Multidrug resistance (MDR) is one of curses on oncotherapy study in recent years,the mechanisms of which are intricate extremely. 肿瘤多药耐药(MDR)是近年来肿瘤治疗研究的困扰之一,其产生机制非常错综复杂。
- Abstract: Multidrug resistance (MDR) is one of curses on oncotherapy study in recent years,the mechanisms of which are intricate extremely. 摘要: 肿瘤多药耐药(MDR) 是近年来肿瘤治疗研究的困扰之一,其产生机制非常错综复杂。
- Multidrug resistance (MDR) is the most common cause in the failure of cancer chemotherapy.Drug transporters play an important role in multidrug resistance in cancer. 多药耐药性(MDR)是肿瘤化疗失败的最常见原因,药物转运蛋白在肿瘤多药耐药性中产生了重要的作用。
- A significant impediment to the success of cancer chemotherapy is multidrug resistance (MDR)and this could be attributable to concomitance of multiple intricate mechanisms. 肿瘤多药耐药(MDR)是导致肿瘤化疗失败的主要原因之一,是多种复杂机制共同作用的结果。
- Multidrug resistance(MDR) has become the main hindrance of chemotherapy,and the reversal of MDR is the key point to improve curative effect of chemotherapy. 摘要 肿瘤细胞对化疗药物产生的多药耐药(MDR)已成为当前影响肿瘤化学治疗疗效的主要障碍,寻找低毒有效的MDR逆转剂是提高化疗疗效的关键。
- The aim of this study was to ex amine the reversal effects of high intensity focused ultrasound (HIFU) and co-a dministration with Adriamycin (ADM) on multidrug resistance (MDR) in HepG2/Adm c ells, and to investigate its mechanism. 本研究评价高强度聚焦超声及其联合阿霉素(Adriamycin,ADM)对人肝癌多药耐药细胞株HepG2/Adm的效应,并探讨其作用机制。
- Objective To study the effect of hyperthermia on expression of multidrug resistance-related(MDR) proteins and intracellular ADM concentration in tongue squamous cell carcinoma cell line Tca 8113 and its multidrug resistance(MDR) cell line Tca8113/CBDEA. 目的探讨热疗对舌鳞癌Tca 8113细胞和耐药的Tca 8113/CBDEA细胞多药耐药蛋白表达和耐药性的影响。
- Objective: To investigate the relationship between the expression of lung resistance-related protein (LRP)gene and multidrug resistance (MDR)in patients with acute myeloid leukemia(AML). 目的:探讨肺耐药相关蛋白(Lung reristance-related protein,LRP)基因在急性髓性白血病(Acute myeloid Leukemia,AML)细胞中的表达及其在临床耐药、预后判断方面的意义。
- Objective:To study effect of radiotherapy on expressions of multidrug resistance(MDR) factors and intracellular ADM concentration in tongue squamous cell carcinoma cell line Tca 8113 and its MDR cell line Tca8113/CBDEA. 目的:探讨放疗对舌鳞癌Tca 8113细胞和耐药的Tca 8113/CBDEA细胞耐药性的影响。
- AIM: To study the reversal effects of droloxifene (DRO) on multidrug resistance (MDR) in K562 cell line resistant to adriamycin (ADR). 目的:研究屈洛昔芬(DRO)对耐阿霉素(ADR)K562细胞株(K562/A02)多药耐药性(MDR)的逆转作用及逆转机制。
- Although P gp expression is not the only mechanism of MDR, but determination of P gp expression might be helpful in making effort to overcome multidrug resistance of bladder cancer. 尽管P-gp表达不是引起多药耐受性的唯一机理,但它对克服膀胱癌的抗药性具有重要的临床价值。
- Obsjective:To observe the reversal effect of Sangen Mixture(SGM) in multidrug resistant(MDR) cell lines K562/ADR and K562/VCR. 目的:研究三根制剂对多药耐药(MDR)细胞株的逆转作用。
- Conclusion PKC expression was closely related to multidrug resistance phenotype.PKC is probably an important modulator in adjusting MDR expression in renal pelvic and ureteral carcinoma. 结论蛋白激酶C与肾盂输尿管癌多药耐药密切相关,可能是调节肾盂输尿管癌多药耐药的重要因素之一。