Methods Eighty male SD rats were randomly divided into sham group(n=40)and bleomycin group(BLM,n=40),in which SD rats were injected with a single intratracheal dose of sham saline or bleomycin respectively.

• 方法雄性SD大鼠80只,随机分为假手术组(n=40)和博莱霉素组(BLM组,n=40)。 向BLM组大鼠气管内一次性注入BLM复制肺纤维化模型,假手术组大鼠则在气管内注入等量生理盐水。