Methods Starting with 3-fluorophenyl isocyanate and(R)-epichlorohydrin, linezolid was synthesized through cyclization, substitution, acylation, bromination, and condensation.

• 方法以(R)-环氧氯丙烷和间氟苯基异氰酸酯为起始原料，经环化、叠氮化、还原、酰化、溴代、缩合反应得到利奈唑酮。