Methods The bioactivity of the same reteplase sample was assayed by four methods of clot lysis assay,fibrin plate assay,chromogenic substrate assay and bubble assay, respectively.

• 方法分别使用凝块溶解法、平板溶圈法、发色底物法及气泡法4种方法,测定同一批瑞替普酶样品的生物活性。