Methods The expression of CD147,MMP-9 and p-ERK was immunohistochemically examined in 96 cases of IDC of breast,34 cases of ductal carcinoma in situ(DCIS) and 10 cases of breast adenosis.

• 方法应用免疫组化EnvisionTM二步法检测96例乳腺浸润性导管癌(invasive ductal carcinoma,IDC)、34例导管内癌(ductal carcinoma in situ,DCIS)及10例乳腺腺病中CD147、MMP-9及p-ERK蛋白的表达,并分析其与临床病理参数的相关性。