OBJECTIVE : The tubulointerstitial fibrosis(TIF) and progressive deterioration of the renal impairment are almost the common pathway by which all the kidney diseases progress to end stage renal failure.

• 目的:肾间质纤维化导致肾脏损害进行性发展,几乎是所有肾脏疾病进展至终末期肾功能衰竭的共同途径。