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- Rat Phosphotylinosital 3 kinase，PI3K Elisa Kit... 大鼠磷酸肌醇3激酶（PI3K）试剂盒；
- In the integrin-signal transduction pathway which FAK is central, except for the ras-MAPK pathway, there are also phosphatidylinositol-3-kinase (PI3K) and protein kinase B (serine/threonrine kinase, AKT) signal molecules. 以FAK为中心的整合素信号转导通路除了ras-MAPK信号途径外,还有磷脂酰肌醇-3激酶(phosphatidylinositol 3-kinase, PI3K)和蛋白激酶B即AKT(serine/threonrine kinase,AKT)信号分子的参与。
- The insulin works by switching on cellular signaling proteins called kinases (specifically Src, PI3K, and Akt) and a protein (SREBP) that binds elements in DNA that regulate the production of cholesterol and its relatives. 胰岛素功能在于激活一类叫作激酶的细胞信号蛋白（特定的致敏反应细胞，如磷脂酰肌醇(-3)激酶,蛋白激酶B等）以及一种DNA元素结合蛋白（胆固醇调节元件结合蛋白），这种蛋白质能调节胆固醇及类胆固醇的生成。
- The lipid kinase phosphoinositied 3-OH kinase(PI3K) and its downstream target AKT,that is protein kinase B(PKB),plays important roles in carcinogenesis signal pathway reduced by kinds of PTK receptor. 脂类激酶PI3K和它的下游靶点Akt,即蛋白激酶B,在各种酪氨酸激酶受体诱导的致癌信号通路中发挥了重要的作用。
- Low-expression of PTEN protein may stimulate overexpression of PI3K protein. PTEN表达的缺失可能刺激了PI3K蛋白的强阳性表达。
- Kenyan buyer requires suspension parts for mtor vehicles, clutches and pressure plates, silicone andar care products, motorcycle helmets, brake pads, fan belts, etc. Korean supp. 中文内容:我方求购韩国产的汽车配件,主要有:离合器,压力器,摩托车头盔,刹车等。有意者,请邮寄目录表及价目表!
- The phosphorylation of Akt and FAK were dramatically attenuated in cells treated with rosiglitazone. 由于FAK和Akt都是抑癌基因PTEN（phosphatase and tensin homolog deleted on chromosome ten）的下游信号分子，因此我们检测了ROS对PTEN的影响，结果发现ROS可以上调PTEN蛋白质，而且这种上调作用具有剂量和时间依赖性；
- Liu Yi,He Yikang,Qin Feng,et al.Investigation of mtor saliency tracking based sensorless vector control drive for PMSM[J].Proceedings of the CSEE,2005,25(17):121-126(in Chinese). [7]刘毅;贺益康;秦峰;等.;基于转子凸极跟踪的无位置传感器永磁同步电机矢量控制研究[J]
- In wild-type adult mice, the mTOR activity was suppressed and new protein synthesis was impaired in axotomized RGCs, which may contribute to the regeneration failure. 而且，在存活下来的样本中，多达10%25显示出了明显的神经轴突再生。这种再生随时间延长而不断增加。
- We know that glutamate activates mGluR and PI3K, but we don't know how, he said. 我们知道谷氨酸激活亲代谢性谷氨酸盐受体和PI3K，但并不知道机理，他说到。
- However, interfering with PI3K signaling might increase the risk of bacterial infections in humans. 但是干扰PI3K信号通路可能会增加患者细菌感染的机会。
- Methods: Immunohistochemistry(SP method) was adopted to detect PTEN and PI3K protein expression levels. 方法:采用免疫组织化学SP法检测PTEN与PI3K的蛋白表达。
- Results: PTEN and PI3K proteins positive rates were 55.93%(33/59) and 77.97%(46/59) respectively in 59 NSCLC. 结果：NSCLC组织中PTEN、PI3K蛋白的阳性表达率分别为55.;93%25(33/59)、77
- Howeer, interfering with PI3K signaling might increase the risk of bacterial infections in humans. 但是干扰PI3K信号通路可能会增加患者细菌感染的机会。
- Akt is one of Ser (serine)/Thr (threonine) protein kinases, which occupies hinge location in these signal transductions. Akt2 is one member of Akt family. Akt是一种丝氨酸/苏氨酸蛋白激酶，处于该信号转导的枢纽部位，Akt2是Akt的亚型之一，更多地参与了人类肿瘤的发生和发展。
- Conclusion: The pathway of signal transcription after insulin receptor can be affect by leptin through PI3K pathway. PI3K途径 Part 1 Expression and Distribution of the Functional Leptin Receptor mRNA Objective Leptin receptor is a recently identified hormonal product; encoded by the diabetic(db) gene .
- Here we report that AKT associates with NFAR1 in vivo with colocalization in the nucleus of the cell.Experiments in vitro and in vivo shows AKT phosphorylates NFAR1 on Serine 647. 在本文中证实了AKT与NFAR1相互作用的，并共定位于细胞核，并用体外实验和体内实验证明了AKT确实可以磷酸化NFAR1的S 647位。
- Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2a. 通过激活抑癌基因PTEN在抑制癌细胞PI3K途径通过交换因子的P - REX2a。
- Decrease of AKT phosphorylation affects the activity of glucose transporter-4（GLUT-4） which translocates the glucose into cells, so the level of blood glucose increases. AKT磷酸化的降低即活性的降低导致葡萄糖转运因子4（Glucose Transporter-4，GLUT-4）的活性降低，最终影响血液中葡萄糖向细胞内的转运，表现出血糖升高的生理现象。
