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- Objective To evaluate the efficacy and safety of pulmonary surfactant(PS)in the replacement therapy for neonatal respiratory distress syndrome(NRDS). 目的评价肺表面活性物质(PS)替代治疗新生儿呼吸窘迫综合症(NRDS)的疗效及安全性。
- Objective The aim of this study was to determine the therapeutic effect of pulmonary surfactant (PS) on the development of bronchopulmonary dysplasia (BPD) in premature infants. 目的探讨肺表面活性物质(PS)对支气管肺发育不良(BPD)的预防和治疗意义。
- AIM To investigate the ruthenium red (RR) staining on the visualizing of ultrastructures of pulmonary surfactant (PS) in injured lungs caused by bleomycin (BLM). 目的 观察钌红染色方法对博莱霉素 (BL M)肺损伤早期肺表面活性物质 (PS)的超微结构的效果 .
- Previous study showed that ALI/ARDS patients had abnormal pulmonary surfactant(PS)system. PS inducer therapy could ease ALI/ARDS and retain pulmonary function. 有研究表明,ALI/ARDS患者存在内源性肺表面活性物质(PS)系统异常,内源性PS诱导剂治疗对减轻ALI/ ARDS病情、促进肺功能恢复有显著作用,但在百草枯中毒导致的ALI/ARDS中的作用未见报道。
- AIM: To study the change of pulmonary surfactant (PS), lipid peroxide (LPO), and the protective effects of astragalius membranaceus on the ischemia-reperfusion (I/R) injury. 摘要目的:探讨肠缺血-再灌注损伤时,肺表面活性物质及脂质过氧化物(LPO)含量的改变及其意义,以及黄芪在缺血-再灌注过程中对肺损伤的保护作用。
- To research the change of plasma fibronectin (Fn) and pulmonary surfactant (PS) and the effect of 654 2 on the content of Fn and PS in rabbits with pulmonary edema caused by oleic acid. 目的:实验观察油酸型急性肺水肿家兔血浆纤维连接蛋白(Fn)和肺表面活性物质(PS)含量的变化,以及给予山莨菪碱(654-2)后对其变化的影响。
- Pulmonary surfactants(PS) is important to maintain the normal lung function,and surfactant alterations have been implicated in the pathophysiology of acute respiratory distress syndrome(ARDS). 肺表面活性物质(PS)在维持正常的肺功能起着重要作用,业已证明,PS异常与急性呼吸窘迫综合征(ARDS)的发病有关。
- Pulmonary surfactant therapy in premature infants with respiratory distress syndrome. 肺表面活性物质治疗早产儿呼吸窘迫综合征。
- Effect of four mechanical ventilation modes on pulmonary surfactant in early stage after severe smoke inhalation injury in dogs. 机械通气对严重烟雾吸入伤犬早期肺表面活性物质的影响。
- His professional interests include the study of regulation of pulmonary surfactant synthesis, the function of Clara cells, and the molecular mechanisms of acute lung injury. 细胞抗肺纤维化及外周谷氨酸受体过度激活在急性肺损伤发生中作用的研究。
- Objective Pulmonary surfactant protein-D(SP-D) is regarded as a valuable biomarker in acute lung injury(ALI) and acute respiratory distress syndrome(ARDS). 目的肺表面活性物质蛋白D(SP-D)被认为是急性肺损伤(ALI)和急性呼吸窘迫综合征(ARDS)有价值的生物指标。
- Among those, DPPC (Dipalmitoyl Phosphatidylcholine) is the major component which contributes to the surface tension lowering ability of pulmonary surfactant. 在这些成份当中又以DPPC为主要的成份,而DPPC经过证实是降低肺泡界面表面张力的主要成份。
- OBJECTIVE To develop a headspace capillary gas chromatography method for the determination of residual organic solvents in porcine pulmonary surfactant. 目的建立顶空毛细管气相色谱法测定猪肺表面活性物质中的有机溶剂残留量。
- OBJECTIVE To develop a HPLC-ELSD method for the determination of seven phospholipid components in porcine pulmonary surfactant and its lyophilized powder. 目的建立猪肺表面活性物质及其冻干粉中7种磷脂组分的含量测定方法。
- Newborn may get respiratory distress syndrome even to death for deficiency of pulmonary surfactant and formation of pulmonary atelectasis and hyaluronic membrane in alveoli. 初生儿也可因缺乏肺表面活性物质;发生肺不张和肺泡内表面透明质膜形成;造成呼吸窘迫综合征;导致死亡.
- The pathogenesy of smoke inhalation acute lung injury/acute respiratory distress syndrome(ALI/ARDS) is not completely clear,perhaps concerned with oxidative damage,the change of pulmonary surfactant and cytokine,and apoptosis. 目前烟雾吸入性急性肺损伤(ALI)/急性呼吸窘迫综合征(ARDS)的发病机制尚未完全明确,可能与烟雾所致的氧化性损伤、肺表面活性物质变化、细胞因子改变、细胞凋亡的发生有关。
- Lining at the air-liquid interface, pulmonary surfactant is a complex mixture of 90% lipids and 10% proteins. The major phospholipid (75%) is dipalmitoylphosphatidylcholine (DPPC) . 位于肺的液气交界面的肺泡表面活性物质由大约90%25的脂质和10%25的蛋白质组成,脂质中90%25为磷脂,主要(75%25)是二棕榈酰磷脂酰胆碱(dipalmitoylphosphatidylcholine,DPPC)使得肺泡呼气末表面张力较小。
- Keywords Pulmonary surfactant (PS);Premature;Neonatal respiratory distress syndrome(NRDS); 肺表面活性物质(PS);早产儿;新生儿呼吸窘迫综合征(NRDS);
- pulmonary surfactant protein A like molecules 肺表面活化蛋白A相似分子
- pulmonary surfactant replacement 肺表面活性剂替代物