SKI can increase the G0/G1 ratio gradually, decrease the cell ratio in S period, and prevent cells access to S period from G1 period as well promote their apoptosis, and the effects of high-dose group and moderate-dose group are better than Lotensin.

• SKI能使大鼠KFB G_0/G_1期细胞比逐渐增高，S期细胞比降低，阻滞细胞由G_1期进入S期，并促进其发生凋亡，其高、中剂量组的作用均优于洛汀新。