Stereoselectivities were observed in enzymatic affinity(Km),maximum reaction speed(Vmax) and intrinsic clearance (Clint).

• 普萘洛尔R（＋ ）和S（－ ）两种对映体在两种鼠肝微粒体的体外孵育葡醛酸缀合代谢中，酶与底物亲和力、最大反应速度和内在清除率均表现出立体选择性。