The adaptation of infectious bursal disease virus (IBDV) B 836 F 4 to Vero cells was studied.

• 传染性法氏囊病病毒疫苗的传统生产工艺是利用鸡胚成纤维细胞增殖 IBDV；但易被外源病原污染 ；且生产成本很高 .