The increase of ACh release in the frontal cortex after perfusion of high[K +] solution(100 mmol/L) through the dialysis probe was 30.18% in aged rats, but it was 96% in young rats.

• 老龄大鼠额叶胆碱能神经元对高 [K+ ]溶液的反应较弱 ；乙酰胆碱的释放量仅增加 3 0 .；18%25；而年轻大鼠可增加 96%25。