The mechanism of chloramphenicol toxicityis apparently failure of the newborn to conjugate chloramphenicol with glucuronic aciddue toinadequate activityof hepaticglucuronyl transferase.

• 氯霉素中毒的机制显然是由于新生儿肝脏的葡萄糖醛酸转移酶活性不足,不能使氯霉素与葡萄糖醛酸结合。