The parameters of puberty and growth in high-dose and middle-dose of CHM groups were no differences from the normal group and the leuprorelin group, which were much lower than those in the model group.

• 2)中药大、中剂量组的青春发育指标和生长指标均小于或低于性早熟模型组(P<0.；05)；中药大、中剂量组两者之间差异无显著性(P>0