The present studyindicates that McAb AU1~1 against cervical carcinoma can mediate ADCC of splenocytes,peritoneal macrophages and LAK to U14 cells, suggests that its ability to direct ADCC make thisantibody promising candidate for cervical cancer therapy.

• 该研究表明针对宫颈癌细胞的单克隆抗体AU_(14-1)能通过ADCC发挥淋巴样细胞、巨噬细胞及LAK细胞对靶肿瘤细胞的杀伤作用； 提示特异性宫颈癌单克隆抗体AU_(14-1)介导的抗体依赖细胞介导细胞毒（ADCC）在治疗宫颈癌中可能是一种有希望的方法。