The trouble is that

• 麻烦的是； 困难在于

The trouble is that的用法和样例：

例句

1. His blindness is a great trial to him.
   眼睛瞎对他来说是非常麻烦的事。
2. Knave is usually a person who gets into trouble.
   一个无赖往往意味着他是一个带来麻烦的人。
3. The difficulty is to know what we mean by a virus.
   困难在于懂得病毒指的是什么。
4. The difficulty lies in their poor health.
   困难在于他们的健康状况都不好。