This article reviews the progress of targeting therapy on strategy of prodrug,immunotoxic,gene therapy,targeting to the key molecules in the proliferation and metastasis of tumor,etc.

• 本文综述了前体药物疗法、免疫毒素、基因疗法、以肿瘤增殖转移过程中的关键分子为靶的导向治疗、生物素-亲和素系统等导向治疗的研究进展。