This construction of cells stably secreting human 4IgB7-H3-Fc fusion protein and the purified protein will contribute to further research on the functions of B7-H3.

• 纯化后的4IgB7-H3-Fc蛋白能够与活化T细胞表面结合,并对T细胞有显著的促增殖作用。 为探讨人4IgB7-H3-Fc融合蛋白对T细胞的共刺激作用和寻找其未知受体奠定良好的物质基础。