When HCCLM6 was injected into the subcutis on the back on nude mice, 100% spontaneous pulmonary metastases occurred in 5 weeks, with median number of lung metastases of 145 per mouse.

• HCCLM6接种于裸鼠背部皮下5周后自发性肺转移率为100%25，肺转移灶中位数145个/裸鼠。接种于裸鼠足垫皮下出现淋巴结转移（3/4只）。