The aggrecan locus has been linked to multiple skeletal disorders. 聚集蛋白聚糖基因位点与多种骨科疾病存在联系。
A polymorphism, within the aggrecan gene, was preiously reported to be associated with cure seerity in indiiduals with scoliosis. 存在于聚集蛋白聚糖基因的多态现象被先前报道与脊柱侧弯个体的弯曲严重程度存在联系。