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- The gene silence of XAF1 is related with the hypermethylation of its promotor. XAF1的基因沉默与其启动子高甲基化明显相关。
- The mechanisms of gene silencing include copy numbers and configuration of transgene, integration sites in plant and transcription of transgene, etc. 基因沉默的机制是多方面的,包括转基因的拷贝数和构型、在植物上的整合位点、转基因的转录水平等。
- Abstract: BACKGROUND: Gene promoter methylation is an epigenetic eent leading to gene silencing. 摘要:背景:基因启动子甲基化是一种可引起基因沉默的表观遗传事件。
- Gene silencing can be divided into two types: position effect and homology dependent gene silencing (HdGS). 基因沉默大体可以分为两类:位置效应引起的基因沉默和同源依赖的基因沉默。
- Gene silencing is a kind of epigenetic phenomenon discovered in transgenic plants in recent years. 摘要基因沉默是近几年来在转基因植物中发现的一种后生遗传现象。
- Finally, the researchers showed that DNMT1-stimulated HP1 binding is required for gene silencing. 最后,研究者指出DNMT1激发性Hp1蛋白的结合作用需要基因沉默。
- Posttranscriptional gene silencing(PTGS) is considered to be one of dominant mechanisms of RNA-mediated resistance. 转录后基因沉默现象是植物抵御病毒入侵、保持自身基因组完整性的一种防御机制。
- RNA interference (RNAi) is a postranscriptional gene silencing (PTGS) mechanism induced by double-stranded RNA (dsRNA). 摘要RNA干扰,是1种由双链RNA引发的转录后基因沉默现象。
- This mutant showed an increased sensitivity to DNA damage and release of transcriptional gene silencing (TGS) in heterochromatin. 这个突变体同时也显现了对DNA损伤的高敏感性以及在异染色质上转录基因沉默(TGS)的释放。
- Abstract:Objective:To observe the effect of PKB gene silencing on the growth of gastric cancer cell line SGC-7901 in vitro. 目的:探讨蛋白激酶B(PKB)基因沉默对人胃癌SGC-7901细胞增殖的作用。
- Posttranscriptional gene silencing (PTGS) in plants is a form of RNA silencing by which target RNA is degraded in a sequence-specific manner. 植物中的转录后基因沉默(PTGS)是RNA沉默的一种形式,通过PTGS能对目标RNA进行特异性降解。
- From long period evolution with plants, plant virus obtains the ability to code gene silencing suppressors against this defense system. 基因沉默系统是植物抵抗病毒侵染的防卫体系,在长期的协同进化过程中,由病毒编码的抑制蛋白可以抵消基因沉默系统的作用。
- TMV CP;different constructs;methylation;post transcriptional gene silencing;watermelon;virus diseases;transformation;resistance. 不同结构形式;甲基化;转录后基因沉默;西瓜病毒病;转基因;抗病性
- EXPRESSION OF CATALASE GENE perA FROM BACILLUS STEAROTHERMOPHILUS IN RECOMBINANT E. COLI 嗜热脂肪芽孢杆菌过氧化氢酶基因perA在大肠杆菌中的高效表达
- SET domain proteins of SUV3-9H family specifically methylate the residue lysine 9 of histone H3, resulting in gene silencing. Su(var)3-9家族的SDP专一甲基化组蛋白3第9位赖氨酸(H3K9),从而导致基因沉默(gene silencing)。
- Transgenic plants with high and stable expression are ideal to get by plant gene engineering, but gene silencing limits their application. 摘要植物基因工程研究是希望获得高稳定表达的转基因植株,而转基因沉默现象却限制了转基因植物的应用前景。
- It degrades mRNA specifically and potently through the mediation of corresponding double-stranded RNA and leads to post-transcriptional gene silencing. 它通过双链RNA的介导特异性地降解相应序列的mRNA,从而导致转录后水平的基因沉默。
- The results suggest that gene silencing may be "an efficient and more specific approach for therapy of liver fibrosis," the report states. 报告指出,得到的结果表明基因沉默可能是“一个有效的和更具体的治疗肝纤维化的方法”。
- With the widely application of transgene technology in the fields of high level biologies, more and more attention was payed to gene silence. 随着转基因技术在高等生物中的广泛应用,转基因沉默受到越来越多的重视。
- These phenomena include gene silencing, DNA methylation, nucleolar dominance, transposable elements activation and genomic imprinting. 表观遗传变异包括基因沉默、DNA甲基化、核仁显性、休眠转座子激活和基因组印记等方面。