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- Fatal lactic acidosis has been reported to patients who received didanosine and other antiretroviral agents. 有报道同时应用核苷类似物的患者可能发生乳酸酸中毒,有时是致命的。
- Didanosine Powder should be used during pregnancy only after discussion with your doctor. 怀孕妇女只有在及其必要时才可使用。
- Particular caution should be exercised when administering Didanosine powder to any patient with known risk factors for liver disease. 慎用于有肝病危险因素的患者。
- Clinical studies of didanosine did not include sufficient numbers of subjects aged 65 years and over to determine whether they respond differently than younger subjects. 药代动力学研究未在大于65岁患者中进行。大部分老年患者肾功能有疾病,应在医生指导下调整剂量。
- HAART is effective in reducing HIV-RNA and improving immune functions at 52 weeks,but the rate of peripheral neuropathy is high by combining Didanosine(ddI) and Stavudine(d4T). HAART治疗取得了较好的疗效,但司他夫定和去羟肌苷联合应用使周围神经病变发生率较高;
- Didanosine powder contain antacid, it can lowers the levels of drugs (eg, Ketoconazole, Itraconazole etc) in the body.So these drugs should be taken two hours before. 吸收后会影响胃液中酸度的药物(如酮康唑、伊曲康唑等),至少须在服用去羟肌苷前2小时服用。
- OBJECTIVE To develop a sensitive and specific LCMS/MS method for the determination of didanosine in human plasma and to study the bioequivalence of different formulations containing didanosine. 目的建立测定人血浆中去羟肌苷的液相色谱-质谱/质谱联用法(LC-MS/MS),并应用于药物制剂生物等效性评价。
- Determination of didanosine by fluorescence quenching 荧光猝灭法测定去羟肌苷的含量
- Keywords didanosine;dorsal root ganglion;neuron;rat; 二脱氧肌苷;背根神经节;神经元;大鼠;
- Keywords Didanosine;Ganglion;spinal;Neurons;Confocal laser scanning microscope; 二脱氧肌苷;神经节;脊;神经元;共聚焦激光扫描显微镜;
- Bioequivalence of domestic and imported didanosine dispersing tablets in healthy volunteers 国产与进口去羟肌苷分散片在健康人体的生物等效性
- Bioequivalence of domestic didanosine powders and imported didanosine tablets in human 国产去羟肌苷散剂与进口去羟肌苷片剂的人体生物等效性
- Determination of Didanosine in Human Plasma and Its Application to a Bioequivalence Study 血浆中去羟肌苷测定与制剂生物等效性评价
- Keywords didanosine;stavudine;quantitative analysis;liquid chromatography-tandem mass spectrometry;pharmacokinetics; 液相色谱-串联质谱法;定量分析;药动学;去羟肌苷;司他夫定;
- Keywords didanosine dispersing tablets;solid phase extraction-HPLC;bioequivalence; 去羟肌苷分散片;固相萃取-高效液相色谱法;生物等效性;
- dideoxycytidinen. 双脱氧胞苷
- didanosinen. 地达诺新
- dideoxycytidine triphosphate 双脱氧胞苷三磷酸
- didanosine (DDI) 去羟肌苷(DDI)
- didanosin 双脱氧腺苷(抗病毒药、核苷类似物化合物)