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- Method: The expression of DDR and its downstream signaling pathways were detected by IHC, WB, RT-PCR and FQ-PCR. 方法:以瘢痕疙瘩组织和KFb为对象,应用IHC、FQ-PCR,WB、RT-PCR研究DDR在瘢痕疙瘩中的表达;
- Focal adhesion kinase (FAK) is a critical mediator that connects integrin and the downstream signal molecules in integrin-signal transduction pathway, and is the convergence of many signal pathways. 黏着斑激酶(focal adhesion kinase，FAK)是整合素信号转导通路中连接整合素与下游信号分子的媒介，处于细胞内多条信号转导通路的交汇点，能激活多条信号转导通路。
- All the NBS-LRR proteins for splice forms may have important function in disease resistance and activate downstream signaling pathways. 这些选择性剪接蛋白可能在抗病信号转导中起到重要作用。
- Focal adhesion kinase (FAK) is the intermediator linking integrins to downstream signal proteins, and plays a key role in multiple signal pathways. 粘着斑激酶（focal adhesion kinase，FAK）则是整合素信号途径中连接整合素与下级信号分子的媒介，是胞内多条信号途径的交汇点。
- Axon Guidance 1: Cues, Receptors, and Downstream Signalling Pathways Dickson, B. J. 轴突引导1:因子,接受器和下游信号传输。
- Main task: Study the immune-related signaling pathway. 主要研究任务：免疫细胞信号传导通路分子机制的研究。
- Scaffold proteins bring together various other proteins in a signaling pathway and allows for their interaction. They recruit downstream effectors in a pathway and enhance specificity of the signal. 支架蛋白是一种在调节信号传导起着重要作用的蛋白质，它通过辅助蛋白激酶和磷酸酶与他们各自的底物结合而起作用。
- The lipid kinase phosphoinositied 3-OH kinase(PI3K) and its downstream target AKT,that is protein kinase B(PKB),plays important roles in carcinogenesis signal pathway reduced by kinds of PTK receptor. 脂类激酶PI3K和它的下游靶点Akt,即蛋白激酶B,在各种酪氨酸激酶受体诱导的致癌信号通路中发挥了重要的作用。
- The ERK signaling pathway is involved in liver fibrosis in many ways. 近年来发现其与肝纤维化的关系密切,可从多方面影响肝纤维化的形成。
- Signaling pathways downstream of pattern-recognition receptors and their cross talk. 信号通路下游的模式识别受体及其相互干扰作用。
- Increasing evidences suggest that signaling pathways downstream of NBS-LRR and NOD proteins are also very similar. 越来越多的研究表明，二者下游的信号通路也非常相似。
- JNK signaling pathway may play an important role in the apoptosis of Eca-109 cells following COPADG treatment. JNK信号转导通路在COPADG诱导Eca-109细胞凋亡过程中发挥重要作用;COPADG通过JNK信号通路诱导Eca-109细胞凋亡.
- LPA exert various biological functions through G protein-coupled receptors and the cellular signaling pathways downstream. LPA通过其受体及耦联的G蛋白调节细胞内信号途径，介导各种生物学效应。
- Taxol-induced apoptosis in RLECS was not mediated by the Eas/EasL signaling pathway. Taxol对RLECs的Fas及FasL基因的表达无明显影响。
- STATs may convert and transmit downstream signal evoked by interaction between cytokines/ growth factors and their ligands. 转录因子STATs能将由细胞因子/生长因子及其受体相互作用激发的下游信号进行协调与转导，同样酪氨酸激酶JAKs也在信号转导途径中起着重要作用，二者调控着细胞的增殖与分化。
- White speculated that the insulin-like signaling pathway in the brain might promote age-related brain diseases. 怀特推测大脑胰岛素样信号途径也许促进与年龄相关的大脑疾病。
- This newly identified signaling pathway opens new therapeutic avenues for the treatment of endothelial dysfunction. 这一最新鉴定的信号通路对治疗内皮功能障碍开辟了新的治疗途径。
- These maturational changes of DCs involved the MyD88-mediated NF-kappaB signaling pathway. 这些树状突细胞的分化改变与MyD88介导的NF-kappaB信号传导途径有关。
- These genes are critical in the signaling pathway for the brain enzyme calcineurin. 这些基因对信号途径中脑钙调磷酸酶很关键。
- These small peptides act as ligands to interact with receptor kinases located on the surface of the cytoplasma membrane, triggering downstream signal transductions. 这些小分子多肽化合物以配基的形式与细胞膜表面的受体激酶相互作用，从而实现细胞之间的信号交流。
