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- Objective To construct the gene vaccine of Coxsackievirus group B type 3(CVB3). 目的探讨构建柯萨奇病毒B组3型(CVB3)基因疫苗的可行性。
- Objective To explore effect of maternal HBV infection on neonatal immunization with hepatitis B gene vaccine. 目的探讨乙型肝炎病毒(BV)染的母亲对新生儿乙型肝炎(称乙肝)因疫苗免疫接种效果的影响。
- Objective To construct a bivalent VP1 gene vaccine against Coxsackie virus B1 and B3 (CVB1 and CVB3) and to test its immunogenicity in mice. 目的 构建柯萨奇病毒 (CV)B1/B3型二价VP1基因免疫质粒 ,并探讨其免疫原性。
- ObjectiveTo study the immunological enhancing effect of human interleukin 15(hIL 15) as gene adjuvant on Coxsackievirus B3(CVB3) VP1 gene vaccine. 目的探讨人白细胞介素 15 (humaninterleukin 15 ,hIL 15 )基因佐剂对柯萨奇B3病毒 (CoxsackievirusB3 ,CVB3 )VP1基因疫苗的免疫增强效果。
- Novel vaccines for veterinary use are the fovus of immunology and virvology.They are mainly subunit vaccines,gene delete vaccines,recombinant viral vaccines,genetic vaccines. 新型兽用疫苗是免疫学和病毒学的研究热点,主要包括亚单位疫苗、基因工程缺失苗、重组病毒活载体疫苗和基因疫苗。
- Methods 40 C57BL/6N mice were divided into 5 groups: Mtb8.4/hIL-12 chimeric gene vaccine, Mtb8.4 gene vaccine, BCG, empty vector alone and PBS. 方法将雌性C57BL/6N小鼠40只;随机分为5组;即Mtb8.;4/hIL-12嵌合基因、Mtb8
- The study was aimed at discussing the effect and significance of immunization of NDV F gene vaccine with chicken IL-18 gene. 本研究的目的是探讨NDV F基因DNA疫苗与鸡IL-18基因联合免疫鸡体的效果及意义。
- Co-immunization of Mtb8.4 gene vaccine and plasmid encoding hIL-12 can enhance the specific cellular immune response induced by the Mtb8.4 gene vaccine alone. hIL-12表达质粒能够增强Mtb8.;4基因疫苗所诱导的细胞免疫应答。
- Keywords genetic vaccine;mastocytoma;RNA replicase; 基因疫苗;肥大细胞瘤;RNA复制酶;
- Immuization with Mtb8.4/hIL-12 chimeric gene vaccine could remarkably reduced CFU counts in organs. Conclusion When it was used to construct the chimeric gene vaccine, hIL-12 could improve the immune efficacy of Mtb8.4 gene vaccine. 结论hIL-12与Mtb8.;4构建成嵌合基因疫苗后;使Mtb8
- The two eukaryotic expression vectors containing GAD65 fragment and IL-10 gene can be successfully constructed, which is a foundation for further development of gene vaccine against type 1 diabetes. 成功构建了2种GAD65片段与IL-10双基因真核表达载体,为1型糖尿病的基因疫苗预防研究提供了实验基础。
- Genetic vaccine represents a new and potentially powerful approach to the development of vaccines, and it has got the success owing to the development of genetic therapy technique. 基因疫苗代表了新的、具有替力的疫苗发展途径和研究方向;它取得成功主要归功于基因治疗技术的发展.
- Genetic vaccines and DNA vaccines are being exploited.The targets are Toxoplasma gondii, pneumocystis carinii, Cryptosporidium parvum, and Angiostrongylus cantonensis. 主要的研究对象为弓形虫、卡氏肺孢子虫、隐孢子虫、广州管圆线虫等。
- In this study, a strain of Recombinant baculovirus can express glycoprotein of RV in mammalian cell was constructed and researched it as antigeng of gene vaccine which can be taken orally. 本实验构建了一株可以在哺乳动物细胞内表达RV糖蛋白的杆状病毒,并对其作为新一代口服基因疫苗的抗原制备进行了探索。
- gosling plague virus VP3 gene vaccine 小鹅瘟病毒vp3基因疫苗
- Objective To investigate the effects of CpG oligodeoxyribonucleotide (ODN) as adjuvants on cellular immune responses in mice immunized with hepatitis B virus (HBV) gene vaccines. 目的 探讨人工合成的含CpG基序的寡核苷酸 (ODN)作为佐剂对乙型肝炎病毒(HBV)基因疫苗诱导小鼠产生细胞免疫应答的影响。
- Screening,cloning,expression,transfer and recombination of immune genes and gene vaccines were expatiated as well. 论述了与免疫功能有关的基因研究,包括免疫基因的筛选、克隆和表达、基因的转移、重组和基因疫苗;
- Construction and identification of chimera genetic vaccine by islet cell tumor associated protein 2 and IgG Fc 胰岛细胞瘤相关蛋白2胞内区与IgG Fc段融合基因疫苗的构建及鉴定
- Basic research and clinical application of gene vaccine 基因疫苗的基础研究及应用现状
- Construction of Somatostatin Genetic Vaccine pcS/SS and Its Expression in HeLa Cells 生长抑素基因疫苗pcS/SS构建及其在HeLa细胞中的表达