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- Phospholipase A2(PLA2)is a family of enzymes which catalyzes the hydrolysis of the special ester bond of phospholipids. 磷脂酶A2是一大类能催化水解磷脂特定酯键的酶,与哺乳动物神经系统存在密切的关系。
- Objective:To demonstrate the role of phospholipase A2 activity (PLA2) on the apoptosis of neutrophiles. 目的:探讨磷脂酶A2(PLA2)活性的变化对中性粒细胞凋亡的影响。
- The hydrolysis of lecithin by phospholipase A2 was firstly studied in vesicle solution and the influence of relevant parameters was investigated. 摘要首次在泡囊水溶液中研究磷脂酶A2催化水解卵磷脂并考察了各种因素对该反应的影响。
- Objective To explore the protective effects of dexamethasone(DXM)-the inhibitor of phospholipase A2(PLA2) on endotoxemia animals. 目的研究磷脂酶A2(PLA2)抑制剂地塞米松(DXM)对内毒素血症动物的保护效应。
- Therefore, phospholipase A2 activity will directly lead to the PC concentration variances in the bile and result in the formation of gallstones. 故磷脂酶A2活性的改变会直接导致卵磷脂浓度发生变化,从而影响胆结石的形成。
- The animals were sacrificed at 24. 48. 72hour under sterile circumstance. The blood samples were collected for analysis of serum amylase(AMY). phospholipase A2 (PLA2). 三组动物分别于术后24、48、72小时无菌条件下活杀取材,腹主动脉取血,送检血淀粉酶(AMY)、磷脂酶A_2(PLA_2)、白介素-6(IL-6)。
- Objective To investigate the effect of polymorphonuclear elastase (PMNE) and phospholipase A2(PLA2) on the acute lung injury in severe acute pancreatitis (SAP). 目的应用大鼠牛磺胆酸钠重症胰腺炎模型探讨粒细胞弹力蛋白酶(PMNE)和磷脂酶A2(PLA2)在重症胰腺炎(SAP)并发急性肺组织损伤中的作用。
- Retkova D H, Monchilova-Pankova AB, Kounanovks, et al.Effect of liver plasma membrane fluidity to endogenous phospholipase A2 activity [J]. Biochem, 1987,69(6): 1251. 商品.;运动中脂质过氧化物对红细胞膜结构和功能的影响[J]
- Cytosolic phospholipase A2 involved in the signal pathway of induction of apoptosis in human umbilical vein endothelial cells by minimally modified low-density lipoprotein. 胞浆型磷脂酶A2介导弱氧化修饰低密度脂蛋白诱导的人脐静脉内皮细胞凋亡。
- Either the A(C15S) chain and B(C55S) chain alone or in combination can not exhibit the phospholipase A2 activity or synaptosome binding activity of b-Bgt. 纯化的A(C15S)链与B(C55S)单独或混和测试时均无明显Phospholipase A2 的酵素活性,同时也无法与Synaptosome 结合。
- Abstract : The effect of calcium ion on the conformation of neutral phospholipase A2(NPLA2) from the venom of Agkistrodon kalys palls was studied by fluorescence spectroscopy. 摘要 : 用荧光光谱方法研究了钙离子对江浙蝮蛇毒中性磷脂酶A2(简称NPLA2)构象的影响。
- The activity of phospholipase A2 (PLA2) and content of Evans blue in tissue and infusing fiuid of rats lung were measured by microtitration. In experiment the tested rats were located under condition simulated 4 000m altitude to 48 hrs. 采用满足法测定了在模拟高原4000m停留48h大鼠肺组织及肺灌洗液的磷脂酶A2活性和伊文思蓝含量的变化。
- Conclusion:Results suggested that the neutrophile apoptosis may be promoted by phospholipase A2 activation,but this process may not be related with PAF,one of the important metabolites of PLA2. 结论:结果表明PLA2激活可促进中性粒细胞凋亡过程,但该过程可能同PLA2的代谢产物血小板激活因子的直接作用无关。
- Objective:To study the concomitant effect of bone morphogenetic protein(BMP) on the activity of the phospholipase A2 (PLA2),which were injected into the lumbar nucleus pulposus of the rabbits to enhance the intervertebral fusion. 目的:探讨腰椎间盘髓核内注射骨形态发生蛋白(BMP)对磷脂酶A2(PLA2)活性的影响。
- Objective To investigate the effect of lidocaine and anisodamine on the alternations of serum amylase,phospholipase A2(PLA2),endotoxin and pathology in acute necrotizing pancreatitis(ANP) rats. 目的探讨利多卡因及山莨菪碱对急性坏死性胰腺炎(ANP)大鼠血淀粉酶、磷脂酶A2、内毒素及其病理学变化的影响。
- Sa G et al. Activation of cytosolic phospholipase A2 by basic fibroblast growth factor via a42Pmitogen activated protein kinase-dependent phosphovylation pathway in endothelial cells[J]. J Biol Chem, 1995,270:2360. 周兰、常英姿、邱宗萌;等.;碱性成纤维细胞因子对缺血/再灌注大鼠心脏的保护作用[J]
- Pretreatment of ECs with phospholipase A2 inhibitor p-bromophenacyl-bromide or cahnodulin antagonist chlorpromazine and aildum ion chelate EGTA obviously decreased H2O2 induced increment of EC-PMN adhesion. 磷脂酶A_2抑制剂对溴苯酰基溴、钙调蛋白抑制剂氯丙嗪和钙离子螯合剂EGTA预处理EC都能显著降低H_2O_2引起的EC-PMN粘附。
- This paper reviews the methods that analyze the positional distribution of fatty acids in triacylglycerol, such as the methods of specific lipase, phospholipase A2, derivatization reagent, HPLC, etc. 综述了甘油三酯中不同位置上酰化脂肪酸的组成及含量的几种测定方法,如专一性脂肪酶法、磷脂酶A2法、衍生化试剂法、HPLC法等。
- This paper reviews the methods that analyze the positional distribution of fatty acids in triacylglycerol,such as the methods of specific lipase,phospholipase A2,derivatization reagent,HPLC,etc. 综述了甘油三酯中不同位置上酰化脂肪酸的组成及含量的几种测定方法,如专一性脂肪酶法、磷脂酶A2法、衍生化试剂法、HPLC法等。
- This thesis presents the role of drugs on activity of phospholipase A2 in the model bile was studied and important information for cholelithiasis in clinical treatment was exhibited. 因此,我们在模型胆汁中研究药物对磷脂酶A2的作用,可为临床治疗胆石病提供重要信息。