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Recent Progress of NorA Multidrug Resistance Pump Inhibitors NorA多药耐药外排泵抑制剂研究进展
To study the mechanism of multidrug resistance in c1inical isolates of Klebsiella pneumoniae and detect the dis-tribution and expression of active efflux pump gene acrAB, homologous to that in Escherichia coli. 目的:研究临床分离多重耐药肺炎克雷伯菌的耐药机制,检测肺炎克雷伯菌中有无类似大肠埃希菌主动外排系统AcrAB的结构基因acrAB的分布和表达。
Progressive familial intrahepatic cholestasis (PFIC) is caused by mutations of the bile salt export pump or the multidrug resistance P-glycoprotein, resulting in chronic hepatic failure. 进行性家族性肝内胆汁淤积症(PFIC)是因为胆盐输出泵或多药耐药性P-糖蛋白突变的结果，常常导致慢性肝功能衰竭。
BACKGROUND & OBJECTIVE: Multidrug resistance is one of the main caus es of treatment failure of chemotherapy. 背景及目的:耐药性产生是化疗失败的主要原因之一,克服耐药性的方法之一是使用逆转剂。
Expression of multidrug resistance gene in patients with maligant trophoblastic tumor and its clinical significance. 多药耐药基因在滋养细胞肿瘤组织中的表达及其临床意义。
Objective To elucidate the multidrug resistance(MDR) in bladdertransitional cell carcinoma. 目的研究膀胱移行细胞癌的多药耐药性。
However, multidrug resistance (MDR) presents an important obstacle for the success of the treatment. 对瘤组织而言,多药耐药是化疗失败的主要原因。
The multidrug resistance rate of positive-integron isolates is far greater than the negative ones. 整合子阳性菌株对多种抗生素的耐药率远大于整合子阴性菌；
The investigate of distribution of integron in multidrug resistance isolates in Jiaozhou Bay was carried out. 摘要为调查整合子在胶州湾水域多重耐药菌中的分布情况。
The invention discloses an application of jamaicin and a structural analog thereof in a reversing multi-drug resistance pump. 本发明公开了小檗碱及其结构类似物在逆转多药耐药泵中的应用。
The mechanism of bacterial efflux pumps is one of the important factors resulting in bacterial multidrug resistance. 细菌耐药性,尤其是多重耐药问题日益严重,给临床治疗带来极大的困难。
Folded filter, filter-tetrafluoroethane, stainless steel filter, and distribution of various types of decay resistance pump. 折叠滤芯，聚四氟滤芯，不锈钢滤芯，，经销各种型号的耐腐泵。
However,the multidrug resistance (MDR) of nasopharyngeal carcinoma is the key role in the failure of the treatment. 而多药耐药(MDR)机制是导致其化疗等综合治疗失败的主要原因。
Multidrug resistance to chemotherapeutic drugs is an important reason for clinical chemotherapy failure. 临床化疗失败的重要原因是肿瘤细胞对化疗药物产生多药耐药(MDR)。
Conclusions The multidrug resistance (MDR) in endometrial carcinoma may be related with the expression of MDR1 gene. 结论子宫内膜癌对化疗的耐药可能是一种固有性MDR,这可能与MDR1基因的表达有关。
Objective To study the relationship between p16,bcl 2 expression and multidrug resistance (MDR) in adenocarcinoma of colon. 目的研究大肠腺癌p16、bcl－2 表达与多药耐药性的关系。
Objective To study the reversal effects of droloxifene (DRO) on multidrug resistance (MDR) in MCF7/ADR and its mechanism. 目的:研究屈洛昔芬(DRO)对乳腺癌耐药细胞株(MCF7/ADR)多药耐药性(MDR)的影响。
Objective: To study the correlation of multidrug resistance protein P170 and active T cell in acute myeloblatlic leukemia(AML). 研究目的：探讨急性髓性白血病耐药蛋白P_(170)与活化T细胞的关系。
The relative quantities of GCS and mdr1 genes in multidrug resistance group were significantly increased compared with non-resistance group(P < 0.001). 急性白血病耐药组标本的GCS基因及mdr1基因的扩增条带吸光度(A)相对比值均明显高于非耐药组(P<0.;001)。
The overexpression of membrane proteins functioning as drug efflux pumps is one of the main mechanisms for multidrug resistance of Candida albicans. 膜转运蛋白高表达导致多药抗药是白念珠菌抗药性产生的最重要机制之一。