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- The procollagen gene expression was analyzed by RT-PCR. PCR用于分析前胶原基因表达。
- The collagen molecule, also known as tropocollagen or collagen monomer, is about 3, 000?? long by 15?? 胶原的分子也称为原胶原或胶原单体物，长约3000?耄0宽15?搿?/UK>
- The collagen molecule, also known as tropocollagen or collagen monomer, is about 3, 000?? long.by 15?? 胶原的分子也称为原胶原或胶原单体物，长约3000?耄
- When the content of tropocollagen is up to 10%, it displays the best elasticity. 当原胶原蛋白含量达10%25时，纤维伸长率最大。
- Changes seen with retinol therapy included an increase in glycosaminoglycan and procollagen in biopsy samples. 使用视黄醇治疗的皮肤活检标本变化检测，包括粘多糖及胶原的增加。
- Immunohistochemical staining showed increased expression of new formed, type I procollagen in keloid tissue. 免疫组化染色显示瘢痕疙瘩中成纤维细胞有丰富的I型前胶原表达。
- Tropocollagen subunits spontaneously self-assemble, with regularly staggered ends, into even larger arrays in the extracellular spaces of tissues. 另外脯氨酸所特有的肽平面夹角也是形成这种特殊螺旋结构的必须因素。
- Bone formation Hydroxyapatite is deposited in nucleation sites between the ends of tropocollagen molecules as the first step in bone formation. 骨骼形成： 骨骼形成的第一步，羧基磷灰石被沉积在原胶原蛋白分子末羰之间的成核部位。
- Objective To compare the procollagen synthesis of patho logical scar-derived fibroblasts from three and two-dimensional culture system . 目的定量分析比较三维及二维培养的病理性瘢痕成纤维细胞内合成的前胶原蛋白。
- Collagen's insolubility was a barrier to study until it was found that tropocollagen from young animals can be extracted because it is not yet fully crosslinked. 胶原蛋白这种特殊的三股螺旋结构保证了它的机械强度。这种三股螺旋被称为原胶原。
- The researchers believe that the increase in glycosaminoglycan enhanced water retention in the skin, while the rise in procollagen levels helped with wrinkle effacement. 研究者认为,粘多糖的增加使皮肤水份保持增强，而不断升高的胶原水平使皱纹消失。
- The skin biopsies showed increased production of glycosaminoglycan and procollagen -- structural components of the skin -- on the arms that receied the retinol lotion. 皮肤活检揭示了涂抹视黄醇润肤乳后，手臂皮肤结构成分中的葡糖胺聚糖和前胶原含量增多。
- Objective To investigate the effects of intense pulse light （IPL） on the content of collagens and mRNA expression of procollagen in BALB/C mouse skin. 目的 研究强脉冲光对BALB/C小鼠真皮内胶原含量以及前胶原基因表达水平的影响。
- The researchers beliee that the increase in glycosaminoglycan enhanced water retention in the skin, while the rise in procollagen leels helped with wrinkle effacement. 研究者认为,粘多糖的增加使皮肤水份保持增强，而不断升高的胶原水平使皱纹消失。
- The skin biopsies showed increased production of glycosaminoglycan and procollagen -- structural components of the skin -- on the arms that received the retinol lotion. 皮肤活检揭示了涂抹视黄醇润肤乳后，手臂皮肤结构成分中的葡糖胺聚糖和前胶原含量增多。
- Epidermal growth factor increases collagen production in granulation tissue by stimulation of fibroblast proliferation and not by activation of procollagen genes. 表皮生长因子通过刺激纤维细胞增殖以增加胶原蛋白在肉芽组织的产生，而非通过激活胶原基因。
- Heat shock protein47(HSP47) is a 47-kDa stress protein that is a collagen-specific molecular chaperone residing in the endoplasmic reticulum (ER). HSP47 is closely involved in the folding, assembly, modification and transport of procollagen. 热休克蛋白47(HSP47)是一种分子量为47KD的蛋白，在内质网中能与多种类型胶原和前胶原特异性结合，HSP47作为胶原合成有关的“分子伴侣”，参与前胶原在内质网中的折叠、装配、修饰和转运等过程，对胶原分子合成质量控制起重要的作用，能够防止错误构型的前胶原分泌出内质网。
- Methods Serum carboxyterminal propeptide of type I procollagen(PICP),carboxytermina telopeptide of type I collagen(ICTP),bone giaprotein(BGP),Calcium(Ca),Phosphorus(P) were measured in 30 of type 2 diabetic patients and 40 controls. 方法 对 30例 2型糖尿病患者及 40例正常人 (对照组 )血清 I型前胶原羧基末端前肽 (PICP)、I型胶原羧基吡啶并啉交联肽 (ICTP)、骨钙素(BGP)、钙 (Ca)、磷 (P)等骨代谢相关指标进行测定。
- Keywords Wound healing;Fibroblasts;Tropocollagen; 伤口愈合;成纤维细胞;原胶原;
- Amino-terminal propeptide of type Ⅱ procollagen 血清型前胶原氨基端肽
